[Breast cancer. current use of the extra-pleural exploration of the internal mammary chain].

The interest to know the Internal Mammary Chain (IMC) Involvement , is that it is a lymphatic filter as primary as the axilla. Anatomic-surgical fundaments, were presented for their exploration. Fifty (50) pectus-sternal, analizing the number of nodes (average 9,7 per specimen), located preferably in the three first intercostal spaces, were studied.

The left ventricle and hemodynamic patterns in essential hypertension.

Hemodynamic patterns in hypertensive patients by radionuclide techniques and tomographic gamma camera were evaluated. In younger hypertensive patients, the hyperkinetic state reflected an increase in heart rate and, consequently, an increased cardiac index and left ventricular ejection fraction (LVEF). Older hypertensive patients, however, showed a different hemodynamic pattern, with reduced systolic and diastolic function at rest compared with normotensive elderly people, and marked depression of cardiac systolic and diastolic reserve during exercise.

Effects of the combination of low-dose nifedipine GITS 20 mg and losartan 50 mg in patients with mild to moderate hypertension.

Most hypertensive patients require more than one medication to effectively control elevated blood pressure (BP) values. This multicenter, randomized, double-blind study was aimed at testing the efficacy and safety of the combination of low-dose nifedipine GITS 20 mg/ losartan 50 mg compared with either monotherapy in patients with grade 1 to 3 hypertension over an eight-week period. Of 352 patients enrolled in the study, 300 were randomized.

Impact of calcium antagonists on the cardiovascular system: experience with lacidipine.

The evaluation of haemodynamic patterns in hypertensive patients by radionuclide techniques and a tomographic gamma camera has revealed differences between older and younger patients. In younger hypertensive patients, the hyperkinetic state is reflected in an increase in heart rate and, consequently, an increased cardiac index and left ventricular ejection fraction (LVEF) in comparison with normotensive controls. Older hypertensive patients, however, show a different haemodynamic pattern, with reduced systolic and diastolic function at rest compared with normotensive elderly people, and marked depression of cardiac reserve during exercise.

Treatment of patients with essential hypertension: amlodipine 5 mg/benazepril 20 mg compared with amlodipine 5 mg, benazepril 20 mg, and placebo.

This multicenter, double-masked, randomized, parallel-group study compared the efficacy, tolerability, and safety of amlodipine 5 mg/benazepril 20 mg, amlodipine 5 mg, benazepril 20 mg, and placebo in patients with essential hypertension. After a placebo run-in period, 308 patients (all white) were randomized to treatment groups and took medication once daily for 8 weeks. Blood pressure was measured after 4 and 8 weeks of treatment in the 23- to 26-hour period after dosing.

Blood pressure control in children of Cordoba, Argentina.

The aims of the present study were 1) to evaluate blood pressure (BP) and its distribution curve in a highly representative population of children and adolescents from Cordoba, Argentina, to determine the normal BP pattern, and 2) to establish the relation between other factors and BP levels. BP data recorded during the years 1984-1987 were evaluated in 280,584 children and adolescents aged 5-15 years (52.1% boys and 47.

Hemodynamic effects of nitrendipine on systolic ventricular function, diastolic ventricular function, and peripheral circulation in essential hypertension.

Twenty patients (aged 33-60 years) with mild to moderate essential hypertension were studied to assess systolic ventricular function, diastolic ventricular function, and peripheral hemodynamic changes induced by nitrendipine during rest and effort, comparing the acute and chronic treatment phases. We used a randomized, placebo-controlled, double-blind, crossover protocol in the acute phase and a paired, placebo group controlled study, with 20 mg single oral daily dose for a 3-week treatment period (chronic phase). The cardiac and peripheral hemodynamic parameters were quantified by noninvasive radionuclides techniques.

[Radiation treatment in advanced cancer of the lung].

This is an attempt to evaluate the results of the radiotherapeutic treatment in patients with advanced lung cancer. The results of a series of 200 patients with lung cancer no oat cell. Average age: 59 years, ranging from 39 to 78, with male frank predominance (174/200).

Lymphscintigraphies of the internal mammary ganglion chain: our experience.

In this study we have evaluated 301 internal mammary lymphoscintigraphies. The results were compared with the histology of internal mammary lymphoscintigraphies, lymphatic chain and axillary lymph nodes, with the anatomo-pathological stage of the disease, with primary tumor site, and also with patients survival. The influence of breast surgery and radiotherapy on the internal breast is shown in the results of the said 301 internal breast lymphscannings.

Diagnostic value of the different methods for evaluation of bone metastasis in breast carcinoma.

A group of 263 patients portraying breast Ca staged through the clinic, is studied and evaluated by different methods of diagnosis as regards bone metastasis. A clinical investigation of bone pain, specific laboratory determinations for Ca-P-alkaline phosphatase; bone X ray, bone scintigraphy with gamma camera are carried on. In some pre-selected cases bone biopsy performed.

Evaluation of severe ventricular arrhythmias in chronic Chagas' heart disease by effort test and Holter monitoring.

The objective of the present study was to evaluate the ability of the gradual effort test (GET) to detect ventricular extrasystoles (VE), and, in particular, to identify patients with high arrhythmic risk in Chagas' heart disease, as well as to compare the results to those obtained by 24 h ambulatory electrocardiographic monitoring (Holter monitoring). A total of 103 Chagasic patients aged 20 to 55 years who exhibited no clinical signs of heart failure or complex arrhythmias under resting conditions were submitted to 24 h Holter monitoring and to a GET with discontinuous loads first applied to reach 120 bpm and then submaximal or maximal heart rate. The results of 24 h ambulatory electrocardiographic monitoring demonstrated that 52.