[Adenogenous cancer of the esophagus].

Bioptates and resected material from patients treated for cancer of the esophagus at the Kazakh Research Institute of Oncology in 1980-1989 were analysed. Adenogenic tumors made up 6.0% of the 1671 cases of esophageal cancer studied.

[Polycystosis of the esophagus].

A rare observation in a male patient of 72 suffering from pulmonary tuberculosis. Severe chronic oesophagitis complicated with polycystosis was found at the autopsy. Multiple retention cysts up to 0.

[Electron microscopic verification of adenocarcinoma of the cardioesophageal area].

Normal gastric and esophageal cardiac glands as well as proper esophageal glands were studied electron-microscopically. Cardiac gastric and esophageal glands were found to differ by chief cells available in the gastric glands and greater amounts of endocrine cells registered in the esophageal glands. The evidence can provide grounds for electron microscopic verification of cardioesophageal adenocarcinoma permitting the pathologist to rest upon the presence of cells resembling those of proper gastric glands and epigastric fossa.

[Electron microscopic study of the histogenesis of dimorphous adenosquamous cell cancer of the esophagus].

The report discusses a comparison of the results of electron microscopic study of glandular-squamous cell carcinoma of the esophagus, normal mucous gland tissues of the same organ and those in reserve cell proliferation. Glandular-squamous cell cancer tissues were found to contain tumor squamous-epithelial cells, glandular cells with secretory grains inherent in the mucous glands proper of the esophagus as well as chimera cells revealing the ultrastructural characteristics of the two cellular type. Further support was obtained for the previously suggested view on the bipotent epithelium of ducts of the mucous glands proper as a source of glandular-squamous cell carcinoma of the esophagus.

[Morphological variants of glandulo-squamous cell cancer of the esophagus].

Microscopical examination of glandular-squamous cell carcinoma of the esophagus (20 cases) showed the variability of its structure. The following morphological varieties of the glandular tumour component are established: tubular, papillary, cystic, mixed. The degree of the tumour component differentiation can vary and this should be reflected in the histological diagnosis.

[Ultrastructure of the esophageal mucus glands in normal conditions and in esophageal cancer].

The ultrastructure of the glandular apparatus and epithelium of the excretory ducts of esophageal mucous glands proper normally and in esophageal carcinoma was studied electron microscopically. Acinar cells were represented by two kinds, "Dark" and "clear" cells reflecting alternating activity of the secretory cells. The ultrastructural features of the reserve cells of excretory ducts such as hypertrophy of the nucleus, scalloped nuclear membrane, high electron density of the nucleus and cytoplasm, abundance of ribosomes and polysomes allow them to be considered as low differentiated highly active cambial elements.

[Adenosquamous cancer of the gallbladder].

The observation of a rare histological form of the gallbladder carcinoma is described. Adenosquamous carcinoma was characterized by the presence of squamous epithelial and glandular components: among the areas of squamous cell carcinoma atypical glands were found which contained also squamous epithelium structures with signs of cell atypiia. The total involvement of the gallbladder, massive necrosis of the tumour, its outgrowth into the liver and dissemination in the peritoneum were observed.

[Morphology of reserve cells of the excretory ducts of esophageal mucous glands in chronic esophagitis].

Morphological, cytophotometrical, and histochemical study of reserve cells of the excretory ducts of esophageal mucous glands in chronic esophagitis was done on autopsy material (189 cases). Chronic esophagites were found to be accompaned by diverse morphological changes of reserve cells manifested in the development of their focal and diffuse hyperplasia. The reserve cells of the esophageal epithelium were found to be capable to differentiate into the squamous and glandular epithelium.

[Esthesioblastoma of the nose].

Morphological investigations of biopsy materials in 8 cases of esthesioblastomas of the nasal cavity were carried out. The three morphological variants of the tumour are described: esthesioneuroepithelioma, esthesioneurocytoma, and esthesioneuroblastoma. Rare occurrence of esthesioblastomas, peculiar features of their histological structure and difficulties of diagnosis in histological verification are emphasized.

[Comparative morphological characteristics of adenoacanthoma of different localization].

A morphological analysis of 40 observations on adeno-acanthomas of different localizations (oesophagus, uterus, larynx, pharynx) is presented. It was established that adeno-acanthoma, which is characterized by two-component composition, distinguished itself by certain variability of the structure. The plano-epithelial component present in the tumour of the glandular structures may be of a different degree of maturation, may have the structure of planocellular cancer, or may have no signs of atypia.