Publications by authors named "Kurt Prenger"
Article Synopsis
- Technical advancements have made sequencing cheaper, allowing large datasets to be generated, but existing tools like Crossbow struggle with large-scale analyses and require significant resources.
- Rainbow, a cloud-based software developed to automate large-scale whole-genome sequencing analyses, can process data from over 500 subjects in just two weeks for under $120 per sample, utilizing Amazon Web Services.
- Rainbow improves upon Crossbow by supporting various input file types, optimizing data load management, logging processing metrics, and merging outputs for easier genome-wide association studies.
Article Synopsis
- RNA-Seq is gaining traction as a more effective alternative to microarrays for analyzing gene expression, bolstered by decreased sequencing costs and a surge in data availability.
- To address the challenges of processing large RNA-Seq datasets locally, a cloud-based tool named Stormbow was developed, which can handle data analysis in parallel, significantly speeding up the process.
- In tests, Stormbow processed samples with 100 million reads in 6 to 8 hours for an average cost of $3.50 per sample, making it a scalable, cost-effective, and user-friendly solution for researchers.
