Effects and side-effects of surgery for snoring and obstructive sleep apnea--a systematic review.

Study Objectives: Many patients undergo surgery for snoring and sleep apnea, although the efficacy and safety of such procedures have not been clearly established. Our aim was systematically to review studies of the efficacy and adverse effects of surgery for snoring and obstructive sleep apnea.

Design: Systematic review.

Cost-effectiveness of primary percutaneous coronary intervention versus thrombolytic therapy for acute myocardial infarction.

Objectives: We sought to determine the long-term cost-effectiveness of two reperfusion modalities in patients with acute ST-segment elevation myocardial infarction: primary percutaneous coronary intervention (PCI) versus thrombolytic therapy.

Design: A state-transition model that follows patients from when they develop STEMI until they die was developed. The model encompassed events and health states.