Publications by authors named "Kuriyama T"

Purpose: The aim of this study was to examine postoperative tilt and decentration after implantation of plate-haptic intraocular lenses (IOLs) after cataract surgery.

Methods: This was an observational retrospective study in which we analyzed the medical records of patients who underwent phacoemulsification with aspiration followed by the implantation of either a plate-haptic IOL (LS-313 MF15; Santen Pharmaceutical Co., Ltd.

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Background: Drug-induced liver injury (DILI) is a common adverse drug event with limited pediatric data in the literature. This study aimed to use pediatric electronic medical records to assess hepatocellular DILI in pediatric patients who were prescribed liver-injury-inducing drugs.

Methods: The Pediatric Medical Information Collection System (P-MICS) is a centralized database integrating electronic medical records from over 40 medical pediatric centers.

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Background: The impact of radiation exposure on cataracts and hand skin cancer in orthopaedic and spine surgeons remains understudied. This study aimed to investigate the prevalence of cataracts and chronic hand inflammation in orthopaedic and spine surgeons and to assess their association with radiation exposure.

Methods: A cross-sectional analysis was conducted on orthopaedic and spine surgeons attending the 38th Annual Meeting of the Neurospinal Society of Japan or the 31st Annual Meeting of the Japanese Society for the Study of Low Back Pain.

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Primary bone marrow lymphoma (PBML) is a malignant lymphoma characterized by proliferation of lymphoma cells exclusively in the bone marrow without lymphadenopathy. Despite the dismal prognosis of PBML, it is a very rare lymphoma with limited evidence concerning its pathophysiology, making accumulation of cases important. We herein report three cases of PBML at our institution.

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In recent years, the stable supply of natural rubber has been threatened by a new leaf fall disease (LFD) caused by filamentous fungi. We screened pesticides to control the growth of sp. and sp.

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Background/objectives: Interventional radiology (IR) utilizing X-rays can lead to occupational radiation exposure, posing health risks for medical personnel in the field. We previously conducted a survey on the occupational radiation exposure of IR nurses in three designated emergency hospitals in Japan. Our findings indicated that a hospital with 214 beds showed a higher lens-equivalent dose than hospitals with 678 and 1182 beds because the distance between the X-ray irradiation field and the IR nurse's position of the hospital with 214 beds was shorter than those of 678 and 1182 beds.

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Purpose: Opioid-induced constipation (OIC) is problematic for patients with cancer receiving opioid therapy. Some guidelines recommend initiating regular laxatives at the same time as opioid analgesics. However, the effectiveness of prophylactic laxatives on OIC has not been widely demonstrated.

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A Mn-based sodium-containing layered oxide, P'2-type NaMnO, is revisited as a positive electrode material for sodium-ion batteries, and factors affecting its electrochemical performances are examined. The cyclability of NaMnO is remarkably improved by increasing the lower cut-off voltage during cycling even though the reversible capacity is sacrificed. Furthermore, the use of highly concentrated electrolytes, in which the presence of free solvent molecules is eliminated, effectively suppresses the dissolution of Mn ions, thus enabling stable cycling with >85% capacity retention for 300 continuous cycles.

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Brain functions are mediated via the complex interplay between several complex factors, and hence, identifying the underlying cause of an abnormality within a certain brain region can be challenging. In mitochondrial disease, abnormalities in brain function are thought to be attributed to accumulation of mitochondrial DNA (mtDNA) with pathogenic mutations; however, only few previous studies have directly demonstrated that accumulation of mutant mtDNA induced abnormalities in brain function. Herein, we examined the effects of mtDNA mutations on brain function via behavioral analyses using a mouse model with an A2748G point mutation in mtDNA tRNA.

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Background: Posterior reversible encephalopathy syndrome (PRES) is known as a transfusion-related complication with typically favorable prognosis and no report fatalities. Pathological evaluation of PRES is also scarce.

Case Report: An 88-year-old female with myelodysplastic syndromes (MDS) attended our hospital because of a compression fracture and chronic heart failure with chronic anemia.

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We devised a method to detect the classical swine fever virus (CSFV) in tail-wiped swabs from wild boars. The CSFV gene in swabs was detected with high sensitivity using nested real-time polymerase chain reaction (PCR), which is a combination of reverse transcription-PCR (RT-PCR) and real-time PCR. We compared CSFV gene detection from boar tissue using the conventional and our tail-wiped swab method.

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Article Synopsis
  • * Congenital thrombotic thrombocytopenic purpura (cTTP) was suspected, prompting tests for ADAMTS13 activity, which revealed severely decreased activity but no inhibitors present.
  • * The combination of test results and genetic testing in her family confirmed a diagnosis of cTTP, highlighting the need for careful evaluation of ITP patients for potential cTTP during follow-up.
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Background And Objectives: ABO blood group mismatch between the donor and the recipient can affect the success of the transplant as well as problems with the red blood cells during allogeneic haematopoietic cell transplantation (HCT). However, the impact of the Rhesus (Rh) D mismatch on transplant outcomes in allogeneic HCT has been poorly elucidated.

Materials And Methods: We retrospectively evaluated the impact of the RhD mismatch on post-transplant outcomes in 64,923 patients who underwent allogeneic HCT between 2000 and 2021 using a Japanese registry database.

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With the International Commission on Radiological Protection's (ICRP) reduction in the radiation dose threshold for cataracts, evaluating and preventing radiation exposure to the lens of the eye among interventional radiology (IR) staff have become urgent tasks. In this study, we focused on differences in lens-equivalent dose (H) to which IR nurses in three hospitals were exposed and aimed to identify factors underlying these differences. According to analyses of time-, distance-, and shielding-related factors, the magnitude of the H dose to which IR nurses were exposed could be explained not by time or shielding but by the distance between the X-ray exposure field and the location of the IR nurse.

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Article Synopsis
  • A study was conducted on 233 patients with persistent atrial fibrillation (PeAF) to evaluate the effectiveness of combining ethanol infusion into the vein of Marshall (EIVOM) with radiofrequency (RF) ablation for improving mitral isthmus (MI) block.
  • The results showed that while RF ablation alone achieved MI block in 77.7% of cases, an additional EIVOM was necessary for 22.3% of patients, leading to overall successful MI block in 96.1% of the participants.
  • Follow-up indicated that patients in the EIVOM group had a significantly lower recurrence rate of atrial fibrillation compared to those who only received RF ablation, highlighting the adjunct
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Background & Aims: Ectopic fat deposition is associated with worsening of glycemic control. This study was conducted to determine whether liraglutide reduces ectopic fat deposition, especially in pancreas, in patients with type 2 diabetes (T2D).

Methods: We retrospectively recruited T2D patients who underwent abdominal unenhanced CT scans both before and after administration of liraglutide (N = 13) or glimepiride (N = 29).

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  • * Initial tests for leukemia-related chimeric genes were negative, but karyotyping revealed an inversion in chromosome 16, which led to further analysis confirming the CBFB::MYH11 fusion gene through advanced techniques like FISH and RNA sequencing.
  • * This case demonstrates a rare subtype of the CBFB::MYH11 fusion gene that can result in false-negative findings with standard screening, highlighting the importance of using modified PCR primers, FISH, and RNA sequencing for accurate diagnosis.
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  • Fludarabine-based conditioning regimens in cord blood transplantation (CBT) have varying effectiveness, with the study analyzing five different combinations in 1395 adult patients suffering from myeloid malignancies.
  • The results showed that the combination of fludarabine and melphalan with high-dose total body irradiation (FM140T) had the highest 3-year survival rate (67%), while other regimens had significantly lower rates, indicating FM140T as the most favorable option.
  • These outcomes suggest that survival rates in CBT for myeloid cancers depend greatly on the type and dosage of alkylating agents used alongside fludarabine, with FM140T being recommended over fludarabine/busulfan
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  • Acute myeloid leukemia (AML) is commonly treated with allogeneic hematopoietic cell transplantation (HCT), and new donor options are available for older patients lacking HLA-matched siblings.
  • This study analyzed outcomes from 5,704 AML patients over 50 years old who received HCT from various donor types between 2013 and 2021, focusing on survival and leukemia-free survival (LFS).
  • Findings revealed that donor type did not significantly affect overall survival, but 8/8 allele-matched and unrelated cord blood donors showed better LFS compared to matched sibling donors, while relapse rates were lower for these donor types.
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This is the first report of vestibular examinations before and after the successful treatment of vestibular migraine (VM), a common cause of recurrent vertigo, with calcitonin gene-related peptide (CGRP) receptor inhibitor. We evaluated a 42-year-old female with VM and concomitant probable Meniere's disease, whose headache and dizziness have improved promptly with the administration of erenumab, a CGRP receptor inhibitor. The sensorineural hearing loss in pure-tone audiometry, dysfunctions shown in vestibular examinations (cervical and ocular vestibular evoked myogenic potentials), and mild endolymphatic hydrops shown in gadolinium-enhanced inner ear magnetic resonance imaging, all in the right ear, revealed no change compared with those observed before treatment.

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  • * A study compared outcomes of 83 patients who underwent HSCT using either PTCy-haplo or UCBT, focusing on 1-year overall survival (OS) and failure-free survival (FFS), finding similar OS rates but better FFS in the PTCy-haplo group, especially in patients under 40
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Anorexia nervosa (AN) is a chronic, life-threatening disease with mental and physical components that include excessive weight loss, persistent food restriction, and altered body image. It is sometimes accompanied by hyperactivity, day-night reversal, and amenorrhea. No medications have been approved specific to the treatment of AN, partially due to its unclear etiopathogenesis.

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  • The study examined the use of C-reactive protein to albumin ratio (CAR) as a prognostic marker in adult T-cell leukemia-lymphoma (ATL), analyzing data from 68 patients diagnosed between 2013 and 2017.
  • Results showed that higher CAR levels were linked to worse overall survival, with patients having a CAR above 0.553 surviving a median of 3.94 months compared to 8.37 months for those below this threshold.
  • The findings suggest that CAR could serve as a simple and valuable independent prognostic marker, particularly in patients undergoing chemotherapy.
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Hematologic diseases frequently affect people >60 years old, and allogeneic stem cell transplantation (allo-SCT) is a potentially curative treatment for these patients. Although several multicenter studies proposed the risk assessment of allo-SCT for the elderly, they receive different treatments and management at each facility. Therefore, accumulating data from institutions that exhibit relatively the same treatment policy and patient care is important.

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