A modified gum arabic cross-linked gelatin scaffold was developed for cell culture, using oxidized gum arabic to create a biocompatible hydrogel through a Schiff's base reaction.
The scaffold's characteristics, including swelling, cross-linking degree, degradation, and microstructure, were analyzed to assess its suitability.
Cytocompatibility tests showed the scaffold is non-cytotoxic and non-adherent, making it a promising option for generating multicellular spheroids in cell culture.