Automatic Detection and Classification of Epileptic Seizures from EEG Data: Finding Optimal Acquisition Settings and Testing Interpretable Machine Learning Approach.

Deep learning (DL) is emerging as a successful technique for automatic detection and differentiation of spontaneous seizures that may otherwise be missed or misclassified. Herein, we propose a system architecture based on top-performing DL models for binary and multigroup classifications with the non-overlapping window technique, which we tested on the TUSZ dataset. The system accurately detects seizure episodes (87.

Correction to: Evolutionarily novel genes are expressed in transgenic fish tumors and their orthologs are involved in development of progressive traits in humans.

[This corrects the article DOI: 10.1186/s13027-019-0262-5.].

Evolutionarily novel genes are expressed in transgenic fish tumors and their orthologs are involved in development of progressive traits in humans.

Abstract: Earlier we suggested a new hypothesis of the possible evolutionary role of hereditary tumors (Kozlov, Evolution by tumor Neofunctionalization, 2014), and described a new class of genes - tumor specifically expressed, evolutionarily novel () genes - that are predicted by this hypothesis (Kozlov, Infect Agents Cancer 11:34, 2016). In this paper we studied evolutionarily novel genes expressed in fish tumors after regression, as a model of evolving organs. As evolutionarily novel genes may not yet have organismal functions, we studied the acquisition of new gene functions by comparing fish evolutionarily novel genes with their human orthologs.

[Study of tumor-specific expression of some evolutionary new genes].

In this paper we have showed that evolutionary new genes DCD1(Dermicidin), LINC00309 (Long intergenic non-protein coding RNA 309) and CLLU1(Chronic lymphocytic leukemia up-regulated 1) have tumor-specific expression profile. Along with our previously published results this confirms the existence of the phenomenon of TSEEN (Tumor-Specifically Expressed, Evolutionarily Novel).

[The detection of the human immunodeficiency virus antigen in the lymphoid cells of seropositive subjects].

Cells from anti-HIV-positive persons were used in experiments for virus isolation. The RT-activity, viral antigen, nucleic acids, electron microscopic morphology, and infectivity were studied. The data presented allow a conclusion that the virus was isolated.

[Effects of wheat bran on the rate of gastric stump and small intestine evacuation in patients with dumping syndrome after stomach resection].

A total of 65 patients with dumping syndrome after gastric resection were under study. It has been found that addition of 10 and 20 g of wheat bran to semolina porridge significantly (p less than 0.05) inhibits the rate of gastric stump and small intestine evacuation, and in 1/3 of the patients it promotes lowered manifestation and duration of dumping syndrome.

[Effect of different types of food loads on the rate of emptying of the gastric stump in patients with the dumping syndrome after gastric resection].

The influence of carbohydrate, carbohydrate-fatty and protein test breakfasts on the rate of gastric stump evacuation was studied in 62 patients with dumping syndrome of mild and moderate severity, using the x-ray method developed by the authors. It has been established that in patients with dumping syndrome carbohydrate and carbohydrate-fatty food is most quickly evacuated from the gastric stump. Doubled amount of fat in the carbohydrate-fatty breakfast (up to 40 g) induced no significant deceleration in the gastric stump evacuation, moreover, in some cases its evacuatory function was accelerated.

[Effect of cimetidine on the gastric evacuatory function in peptic ulcer patients].

A modified x-ray method was used in 28 patients with peptic ulcer of the duodenum to examine, at an interval of 3 days, the rate of evacuation from the stomach of radiographic contrast capsules ingested together with trial food intakes. Assay of the rate of evacuation from the stomach of the radiographic contrast capsules demonstrated that as compared to controls (without cimetidine), a single oral intake of 200 micrograms cimetidine exerts a statistically significant stimulating effect on evacuation from the stomach of the capsules taken with both semolina and appropriate breakfast. The stimulating effect of cimetidine manifested itself commonly 1 h after food intake.

[Hybridization of low molecular weight nuclear RNA with nuclear RNA and DNA restriction fragments].

Blot hybridization of 125I or 32P labeled 4.5S, U1 or U2 RNAs with EcoRI, HindIII, BamHI or SalG1 restriction fragments of high molecular weight DNA was performed. All these RNAs hybridized with fragments of ribosomal DNA and with 5.

[Functional morphology of the adrenal cortex during the physiological rhythm of sex steroid synthesis].

A method of a quantitative histenzymological analysis was used for determination of the extent of participation of various zones of the adrenal cortex in provision of physiological rhythm of the steroid synthesis. The activity of 3beta-OH-steroid dehydrogenase, glucoso-6-phosphat dehydrogenase, NAD- and NADP-diaphorases, acid and alkaline phosphatases and non-specific esterase was investigated. The data of a histoenzymotological study were compared with the result of biochemical analysis of corticosteroids in the peripheral blood.