Archaeological and molecular evidence for ancient chickens in Central Asia.

The origins and dispersal of the chicken across the ancient world remains one of the most enigmatic questions regarding Eurasian domesticated animals. The lack of agreement concerning timing and centers of origin is due to issues with morphological identifications, a lack of direct dating, and poor preservation of thin, brittle bird bones. Here we show that chickens were widely raised across southern Central Asia from the fourth century BC through medieval periods, likely dispersing along the ancient Silk Road.

Anaplastic large cell lymphoma ALK-positive variant of primary bone lymphoma associated with melanoma.

We describe in detail a case of the anaplastic large cell lymphoma (ALCL) type of primary bone lymphoma, which initially was diagnosed and treated as osteomyelitis. The diagnosis was delayed because of unspecific clinical symptoms and uncertain radiographs and histology. Only relapse of the lymphoma from the same area with involvement of the soft tissue and local lymph nodes allowed to establish a correct diagnosis and start treatment.

Hyperlipoproteinemia(a) and Severe Coronary Artery Lesion Types.

Diffuse atherosclerosis and calcification of the coronary arteries (CA) create serious difficulties for coronary artery bypass grafting (CABG). The aim of this study was to compare demographic indicators, lipids, and clinical results one year after CABG in patients with different phenotypes of coronary artery (CA) disease. In total, 390 patients hospitalized for elective CABG were included in a single-center prospective study.

[In-hospital outcomes of endarterectomy and coronary artery bypass grafting in multiple diffuse lesions of coronary arteries].

Background: According to a series of studies, performing coronary endarterectomy in direct myocardial revascularization increases the risk of myocardial infarction and in-hospital mortality. There are no commonly accepted indications for carrying out endarterectomy, and in clinical practice this technique is used in severe diffuse lesions of coronary arteries.

Aim: The study was aimed at assessing in-hospital clinical outcomes of coronary artery bypass grafting (CABG) with the use of endarterectomy in patients with severe multiple diffuse lesions of coronary arteries.

[Molecular mechanisms of neuroretinoprotection in primary open-angle glaucoma].

Purpose: To evaluate the effectiveness of neuroprotective therapy in patients with primary open-angle glaucoma based on specific biochemical markers of neurotrophy and neurodegeneration.

Material And Methods: In the course of the study, lacrimal fluid (LF) of 23 patients (46 eyes) with stage I-II primary open angle glaucoma (POAG) aged 66.3±10.

[Silentscope - new method of diagnosis and treatment of patients with salivary stone disease. The border need to use].

The authors conducted an analysis of the efficiency of the method of suandokmai for diagnosis and treatment of diseases of the salivary glands. The use of calendarscope allows to establish the absence of stone in the case of salivary colic. In rare cases it is possible to remove the stone without surgical intervention at small dimensions of the calculus.

Measurement of the Neutrino Mixing Angle θ_{23} in NOvA.

This Letter reports new results on muon neutrino disappearance from NOvA, using a 14 kton detector equivalent exposure of 6.05×10^{20} protons on target from the NuMI beam at the Fermi National Accelerator Laboratory. The measurement probes the muon-tau symmetry hypothesis that requires maximal θ_{23} mixing (θ_{23}=π/4).

Effective cancer vaccine platform based on attenuated salmonella and a type III secretion system.

Vaccines explored for cancer therapy have been based generally on injectable vector systems used to control foreign infectious pathogens, to which the immune system evolved to respond naturally. However, these vectors may not be effective at presenting tumor-associated antigens (TAA) to the immune system in a manner that is sufficient to engender antitumor responses. We addressed this issue with a novel orally administered Salmonella-based vector that exploits a type III secretion system to deliver selected TAA in the cytosol of professional antigen-presenting cells in situ.

[Long-term results of endoprosthesis of the hip joint with Plus-Endoprosthetic prosthesis].

An experience and results with using endoprosthesis of the hip joint with Plus-Endoprosthetic prosthesis in 937 (1018 operations) patients were analyzed. The period of follow-up observations was 12 years. Distinctive characteristics of the endoprosthesis are described.

[Antibacterial susceptibility/resistance of Vibrio cholerae eltor clinical strains isolated in the Caucasus during the seventh cholera pandemic].

The data on antibacterial susceptibility and resistance of Vibrio cholerae eltor phenotypes with different sets of the susceptibility or resistance markers conditioning the outbreaks and sporadic cases of cholera in the Caucasus within 1970-1998 are presented. An increase of the number of the Vibrio cholerae phenotypes resistant to tetracycline and chloramphenicol usually used in the treatment of cholera was recorded in 1990-1994 vs. 1970-1989.

[Prevalence of main stomatological diseases in workers of silk factory].

Caries and periodontal diseases among the workers of silk factory, where the professional harmfulness were: discomfort of the microclimate, the intensive noise, psychological loads, bound with the monotonic of labor process, enforced working posture, high bacterial dirty of the rooms, were detected of higher levels diseases as contrasted to the data of the people not working in indicated factory. The necessity of implementation of preventive sanitary-hygienic measures for elimination of the professional harmfulness, and also improvement and advancing the dental help to the workers of silk factory were marked.

[Serological markers of viral infections in patients with rheumatoid arthritis].

The authors carried out serologic examination of 202 patients with rheumatoid arthritis (RA) and 200 healthy persons for detecting of specific markers of infections caused with herpes simplex virus (HSV), cytomegalovirus (CMV), Epstein-Barr virus (EBV), hepatitis B and C viruses (HBV and HCV) and human T-cell lymphotropic retroviruses 1 and 2 (HTLV-1/2). It was demonstrated that detecting frequencies of HBsAg and total antibodies to HTLV-1/2, HSV and CMV among RA patients and healthy persons were practical equal--only anti-EBV were detected more often among RA patients than among healthy persons. But in the same time IgM-antibodies to HSV, CMV and EBV were detected more often among RA patients than among healthy persons.

[Approaches to objective assessment of the individual weight bearing in patients after total endoprosthesis of the hip joint].

An algorithm for the detection of weight bearing on the lower extremity after total endoprosthesis of the hip joint was developed, taking into consideration the parameters of the morphometric structure, type of pathology, method of treatment, the resulting extremity functioning and social and every-day conditions. The individual rehabilitation measures after endoprosthesis were performed in three steps and corrected depending on changes in the parameters in question. The amplitude of movements in the joint after using the method of calculation of the weight bearing on the lower extremity became close to normal in 26 patients after completion of the rehabilitation course and the statistic-dynamic indices of the extremity became stable.

[Rehabilitation of orthopedic patients after hip replacement].

A comparative analysis of the treatment of 120 patients after endoprosthesis for degenerative-destructive diseases of the hip joint was carried on. All the patients were divided into two groups: the main group included 74 patients who underwent a full course of rehabilitation, the control group consisted of 46 patients without rehabilitation. The results of a comparative assessment of the static-dynamic function in the two groups of patients after operation of endoprosthesis have shown the inclusion of an obligatory program of rehabilitation to be expedient for the restorative treatment in addition to the operation of endoprosthesis.

[Biomechanical investigations in the assessment of effectiveness of endoprosthesis].

Based on complex biomechanical investigations the authors have brought out clearly that after endoprosthesis in coxarthrosis patients the biomechanical indices concerned with maintenance of posture and kinematics of walking were markedly improved. The remaining light instability, unsteadiness and tension when standing and walking require strict individualization, sequence, loading of the locomotor apparatus.

[Restorative treatment of degenerative-dystrophic diseases of large joints].

The authors performed courses of treatment with Midocalm in 110 patients according to their original method. It reduced the pain syndrome, increased the volume of movements in the joint and shortened the time of treatment.

[Optimization of diet therapy in patients with gallstones complicated with obesity and impaired glucose tolerance].

It was investigated the influence of a diet with lower glycaemic index on clinico-metabolic parameters in obese patients with gallstones and impaired glucose tolerance. The results investigations indicated that the lowering of glycaemic index and the caloric reduction of diet have a beneficial effects on dynamic of parameters of functional status of liver and gallbladder. It was noted the increase of medical effect of diet in correction of obesity and impaired parameters of carbohydrate and lipid metabolism in this patients in process of dietotherapy.

[Cholera in the Republic of Azerbaijan].

The data characterizing the epidemiological aspects of cholera in Azerbaijan at the period of pandemics I-VI are presented and the specific epidemiological features of pandemic VII of this infection are considered. The study revealed that cholera repeatedly penetrated Russia through the territory of Azerbaijan. The existence of two variants of Vibrio cholerae eltor was substantiated: the epidemic variant having the gene of cholera toxin and the nonepidemic variant having no such gene, which caused, respectively, outbreak and sporadic morbidity in Azerbaijan.

[Effect of food loadings on postprandial glycemia in patients with fatty hepatosis in combination with obesity].

It was investigated the dynamic of postprandial glycaemia in 38 patients with fatty hepatosis and obesity after ingestion of breads, macaroni products, grits and legumes and it was determined its glycaemic index in the present study. These differences in the postprandial glycaemic reaction in observed patients in process of food loading were analyze.