Artifact Reduction in Interventional Devices Using Virtual Monoenergetic Images and Iterative Metal Artifact Reduction on Photon-Counting Detector CT.

Objectives: The aim of this study was to assess the impact of an iterative metal artifact reduction (iMAR) algorithm combined with virtual monoenergetic images (VMIs) for artifact reduction in photon-counting detector computed tomography (PCDCT) during interventions.

Materials And Methods: Using an abdominal phantom, we conducted evaluations on the efficacy of iMAR and VMIs for mitigating image artifacts during interventions on a PCDCT. Four different puncture devices were employed under 2 scan modes (QuantumSn at 100 kV, Quantumplus at 140 kV) to simulate various clinical scenarios.

is implicated in central nervous system, orofacial and maxillofacial anomalies.

Background: Previous studies in mouse, and zebrafish embryos show strong expression in progenitor cells of neuronal and neural crest tissues suggesting its involvement in neural crest specification. However, the role of human transcription factor activator protein 2 ( in human embryonic central nervous system (CNS), orofacial and maxillofacial development is unknown.

Methods: Through a collaborative work, exome survey was performed in families with congenital CNS, orofacial and maxillofacial anomalies.

A Quantitative Comparison Between Human and Artificial Intelligence in the Detection of Focal Cortical Dysplasia.

Objectives: Artificial intelligence (AI) is thought to improve lesion detection. However, a lack of knowledge about human performance prevents a comparative evaluation of AI and an accurate assessment of its impact on clinical decision-making. The objective of this work is to quantitatively evaluate the ability of humans to detect focal cortical dysplasia (FCD), compare it to state-of-the-art AI, and determine how it may aid diagnostics.

In Vitro and In Vivo Antipsoriatic Efficacy of Protected and Unprotected Sugar-Zinc Phthalocyanine Conjugates.

Psoriasis, a chronic immune-mediated skin disorder affecting over 125 million people globally, is characterized by abnormal keratinocyte proliferation and immune cell infiltration. Photodynamic therapy (PDT) remains underutilized in the treatment of psoriasis despite its potential as a promising and effective therapeutic approach. This study aimed to explore the efficacy of zinc phthalocyanine (ZnPc) and its sugar conjugates as potential antipsoriatic agents.

Image quality of abdominal photon-counting CT with reduced contrast media dose: Evaluation of reduced contrast media protocols during the COVID19 pandemic supply shortage.

Rationale And Objectives: Aim of this study was to assess the impact of contrast media dose (CMD) reduction on diagnostic quality of photon-counting detector CT (PCD-CT) and energy-integrating detector CT (EID-CT).

Methods: CT scans of the abdominal region with differing CMD acquired in portal venous phase on a PCD-CT were included and compared to EID-CT scans. Diagnostic quality and contrast intensity were rated.

Outcome of transarterial radioembolization in patients with hepatocellular carcinoma as a first-line interventional therapy and after a previous transarterial chemoembolization.

Purpose: Due to a lack of data, there is an ongoing debate regarding the optimal frontline interventional therapy for unresectable hepatocellular carcinoma (HCC). The aim of the study is to compare the results of transarterial radioembolization (TARE) as the first-line therapy and as a subsequent therapy following prior transarterial chemoembolization (TACE) in these patients.

Methods: A total of 83 patients were evaluated, with 38 patients having undergone at least one TACE session prior to TARE [27 male; mean age 67.

Use of virtual monoenergetic images for reduction of extensive dental implant associated artifacts in photon-counting detector CT.

Aim of this study was to assess the impact of virtual monoenergetic images (VMI) on dental implant artifacts in photon-counting detector computed tomography (PCD-CT) compared to standard reconstructed polychromatic images (PI). 30 scans with extensive (≥ 5 dental implants) dental implant-associated artifacts were retrospectively analyzed. Scans were acquired during clinical routine on a PCD-CT.

Comparing accuracy in voice-based assessments of biological speaker traits across speech types.

Nonverbal acoustic parameters of the human voice provide cues to a vocaliser's sex, age, and body size that are relevant in human social and sexual communication, and also increasingly so for computer-based voice recognition and synthesis technologies. While studies have shown some capacity in human listeners to gauge these biological traits from unseen speakers, it remains unknown whether speech complexity improves accuracy. Here, in over 200 vocalisers and 1500 listeners of both sexes, we test whether voice-based assessments of sex, age, height and weight vary from isolated vowels and words, to sequences of vowels and words, to full sentences or paragraphs.

Studying the DNA damage response pathway in hematopoietic canine cancer cell lines, a necessary step for finding targets to generate new therapies to treat cancer in dogs.

Background: Dogs present a significant opportunity for studies in comparative oncology. However, the study of cancer biology phenomena in canine cells is currently limited by restricted availability of validated antibody reagents and techniques. Here, we provide an initial characterization of the expression and activity of key components of the DNA Damage Response (DDR) in a panel of hematopoietic canine cancer cell lines, with the use of commercially available antibody reagents.

Unilateral Non-Hemorrhagic Adrenal Infarction in Pregnancy: Case Series and Literature Review.

To summarize the evidence on non-hemorrhagic adrenal infarction (NHAI) and identify questions arising in diagnosis and management, cases in the PubMed database were merged with our case series. A total of 92 publications were retrieved, 15 of which reported on NHAI during pregnancy. Including the four in our case series, 24 cases have been described so far.

Combining iterative metal artifact reduction and virtual monoenergetic images severely reduces hip prosthesis-associated artifacts in photon-counting detector CT.

Aim of this study was to assess the impact of virtual monoenergetic images (VMI) in combination and comparison with iterative metal artifact reduction (IMAR) on hip prosthesis-associated artifacts in photon-counting detector CT (PCD-CT). Retrospectively, 33 scans with hip prosthesis-associated artifacts acquired during clinical routine on a PCD-CT between 08/2022 and 09/2022 were analyzed. VMI were reconstructed for 100-190 keV with and without IMAR, and compared to polychromatic images.

Microstructure and Corrosion Behavior of ZnAl12Mg3Si0.3 Double-Batch Hot-Dip Coatings.

This article presents the microstructure (SEM) and corrosion behavior of ZnAl12Mg3Si0.3 (ZAMS) coatings obtained by the double hot-dip method on Sebisty steel with increased strength. On the basis of chemical composition studies in micro-areas (EDS) and phase composition studies (XRD), structural components of the coating and corrosion products formed on the coating surface after exposure to the neutral salt spray (NSS) test (EN ISO 9227) were identified.

The Impact of Proinflammatory Cytokines and Imiquimod on GLUT1 in HaCaT Keratinocytes - a Potential Anti-Psoriatic Therapeutic Target?

Background/aims: Glucose metabolism has been proven as an essential process for proliferating keratinocytes, which highlights the importance of glucose transporter-1 (GLUT1) not only in the onset of psoriasis but also in the progression and severity of this inflammation-driven disease. In this study, we attempted to find a connection between proinflammatory cytokines (IL-6, IL-17, IL-23, IL-36, TNF-α), a skin inflammation inducing agent - imiquimod (IMQ) and GLUT1 expression.

Methods: Human keratinocyte HaCaT cell line was incubated with exogenous cytokines: IL-6, IL-17A, IL-23, IL-36, TNF-α at a final concentration of 100 ng/ml, or with 1 µM of IMQ, for 48 h.

[Acute limb ischemia : Quick review for residents in interventional radiology].

Background: Knowledge of diagnosis and treatment of acute limb ischemia is essential to preserve limb viability and prevent irreversible damage.

Objective: A brief review of treatment options, patient selection, and management in acute limb ischemia is provided for residents in interventional radiology.

Methods: The most commonly used interventional treatment options in acute limb ischemia including case studies and recommendations are provided.

Uterine Artery Pseudoaneurysm after an Uncomplicated Vaginal Delivery: A Case Report.

Uterine artery pseudoaneurysm (UAP) is a rare and potentially life-threatening vascular anomaly caused by inadequate sealing of a ruptured wall of a uterine artery. It mainly occurs after a traumatic lesion and can lead to delayed postpartum hemorrhage. We report a rare case of UAP after an uncomplicated vaginal delivery in a patient with a history of deep-infiltrating endometriosis.

Do Voice-Based Judgments of Socially Relevant Speaker Traits Differ Across Speech Types?

Purpose: The human voice is a powerful and evolved social tool, with hundreds of studies showing that nonverbal vocal parameters robustly influence listeners' perceptions of socially meaningful speaker traits, ranging from perceived gender and age to attractiveness and trustworthiness. However, these studies have utilized a wide variety of voice stimuli to measure listeners' voice-based judgments of these traits. Here, in the largest scale study known to date, we test whether listeners judge the same unseen speakers differently depending on the complexity of the neutral speech stimulus, from single vowel sounds to a full paragraph.

Percutaneous transhepatic biliary drainage: a retrospective single-center study of 372 patients.

Background: Complication rates in percutaneous transhepatic biliary drainage (PTBD) are non-uniform and vary considerably. In addition, the impact of peri-procedural risk factors is under-investigated.

Purpose: To compare success and complication rates of PTBD in patients with and without accompanying technical risk factors.

The cannabinoid receptors system in horses: Tissue distribution and cellular identification in skin.

Background: The endocannabinoid system (ECS) is composed of cannabinoid receptors type 1 (CBR1) and type 2 (CBR2), cannabinoid-based ligands (endogenous chemically synthesized phytocannabinoids), and endogenous enzymes controlling their concentrations. Cannabinoid receptors (CBRs) have been identified in invertebrates and in almost all vertebrate species in the central and peripheral nervous system as well as in immune cells, where they control neuroimmune homeostasis. In humans, rodents, dogs, and cats, CBRs expression has been confirmed in the skin, and their expression and tissue distribution become disordered in pathological conditions.

Pilot Animal Study on Robotic-Assisted Endovascular Visceral Interventions.

Purpose: To evaluate technical feasibility and safety of common endovascular visceral interventions using a vascular robotic platform through preclinical study.

Material And Methods: The CorPath GRX Robotic System (Corindus Inc, Waltham, Massachusetts) was tested in an anesthetized pig for its ability to navigate various commercially available devices in the abdominal vasculature and to perform routine endovascular visceral procedures. After manually placing a guiding catheter in the celiac trunk, several visceral branches were probed with microcatheters and -wires under robotic assistance, and embolization with liquids (lipiodol), detachable coils and plugs were performed.

Assessment of liver cirrhosis severity with extracellular volume fraction MRI.

We aimed to investigate the diagnostic utility of MRI extracellular volume fraction (ECV) for the assessment of liver cirrhosis severity as defined by Child-Pugh class. In this retrospective study, 90 patients (68 cirrhotic patients and 22 controls), who underwent multiparametric liver MRI, were identified. Hepatic T1 relaxation times and ECV were assessed.

In Vitro Evaluation of Acrylic Adhesives in Lymphatic Fluids-Influence of Glue Type and Procedural Parameters.

To evaluate the embolic properties of different acrylic adhesive/iodized oil mixtures for lymphatic interventions. Polymerization of histoacryl (HA) (Bayer Healthcare) and glubran 2 (GL) (GEM) mixed with iodized oil (ratios 1:0-1:7) were investigated in lymphatic fluids with low and high triglyceride (low TG & high TG) contents. Static polymerization time and dynamic polymerization experiments with different volumes of glucose flush (1, 2 and 5 mL) were performed to simulate thoracic duct embolization.