The high sampling rate in modern digital systems generates a large scale of data. To address the computational burden, this paper proposes a threshold activation-based simplified Lv's transform (SLVT) algorithm to analyze the transient multi-component linear frequency modulation signals. Only the signal arrival can trigger the signal analysis.
View Article and Find Full Text PDFMicromachines (Basel)
May 2022
The surface of a centrifugal microfluidic immunoassay system chip such as polymethyl methacrylate (PMMA) is often hydrophobic, which leads to problems such as poor liquid transfer efficiency and easy-to-block siphon channels, leading to bad fluid control. Therefore, surface hydrophilic modification for such chips is necessary to improve the rapidity and sensitivity of the system. Chemical modification is commonly used, but there is little research on the hydrophilic effect of different concentrations of hydrophilic reagents.
View Article and Find Full Text PDFElectrophoresis
November 2022
As the medical community puts forward higher requirements for the speed and convenience of disease diagnosis, point-of-care testing has become a hot research topic to overcome various kinds of healthcare problems. Blood test is considered to be highly sensitive and accurate in clinical diagnosis. However, conventional plasma separation system tends to be bulky and needs professional operations.
View Article and Find Full Text PDFTo satisfy the input bandwidth and sampling rate requirements of data acquisition systems, digital bandwidth-interleaved analog-to-digital converters (DBI-ADCs) offer a practical parallel structure. However, the existing DBI-ADC correction methods are broadly inadequate in terms of design, testing, and implementation. Moreover, the evaluation and correction of the most significant feature of the DBI-ADC structure-wideband acquisition performance-is also imperfect.
View Article and Find Full Text PDFRapid diagnosis plays a vital role in daily life and is effective in reducing treatment costs and increasing curability, especially in remote areas with limited availability of resources. Among the various common methods of rapid diagnosis, centrifugal microfluidics has many unique advantages, such as less sample consumption, more precise valve control for sequential loading of samples, and accurately separated module design in a microfluidic network to minimize cross-contamination. Therefore, in recent years, centrifugal microfluidics has been extensively researched, and it has been found to play important roles in biology, chemistry, and medicine.
View Article and Find Full Text PDFIn recent years, point-of-care testing has played an important role in immunoassay, biochemical analysis, and molecular diagnosis, especially in low-resource settings. Among various point-of-care-testing platforms, microfluidic chips have many outstanding advantages. Microfluidic chip applies the technology of miniaturizing conventional laboratory which enables the whole biochemical process including reagent loading, reaction, separation, and detection on the microchip.
View Article and Find Full Text PDFThe time-interleaved (TI) structure has been widely implemented in high speed, wideband data acquisition systems to increase the system sampling rate. However, the frequency responses of each sub-sampling path are not identical. This is named frequency response mismatches (FRMs).
View Article and Find Full Text PDFTime interleaving (TI) technique is widely used in acquisition systems to improve the sampling rate. However, as a parallel sampling structure, it inevitably brings in channel mismatches, such as the offset mismatch, gain mismatch, and time mismatch. Moreover, the gain mismatch and time mismatch are frequency-dependent, which means that the gain mismatch and time mismatch will be different when the signal frequency changes.
View Article and Find Full Text PDFThis paper studies the synchronization between the analog and digital local oscillators (LOs) in bandwidth-interleaved (BI) data acquisition systems (DAQS). It gives a detailed analysis of the random synchronization phase difference between the analog and digital LOs in the BI-DAQS among different acquisition frames. Exploiting the synchrony relation between the analog LO and sampling clock of the BI-DAQS, the synchronization between analog and digital LOs, where the digital LO is generated in the sampling clock domain, in each acquisition frame is realized in the Field Programmable Gate Array (FPGA).
View Article and Find Full Text PDFBecause of the exponential increase of sampling rate, time-interleaved analog-to-digital converter (TIADC) has a fast growth in the high-speed applications. However, the channel mismatch error is a serious challenge for the performance of TIADC. In this article, we address the timing skew mismatch error and propose a novel adaptive calibration method.
View Article and Find Full Text PDFRev Sci Instrum
January 2019
The main factors that enable capture of complex and transient signals in real-time are improved sampling rates and processing speeds. The time-interleaved architecture is an effective method that allows systems to break through the speed bottleneck of single analog-to-digital converters (ADCs) and go beyond the state-of-the-art process technology limit. However, the performance of the acquisition system may be reduced because of the offset, gain, and time mismatch errors that occur in time-interleaved ADC systems.
View Article and Find Full Text PDFIn traditional digital storage oscilloscope (DSO), sampled data need to be processed after each acquisition. During data processing, the acquisition is stopped and oscilloscope is blind to the input signal. Thus, this duration is called dead time.
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