Publications by authors named "Kuocheng Yan"
Infect Drug Resist
July 2024
Article Synopsis
- The infection affects about 50% of people globally, leading to chronic gastritis and gastric cancer, and resistance to antibiotics like clarithromycin complicates treatment efforts.
- A new method called SHIELD was developed for simultaneously detecting the infection and clarithromycin resistance, utilizing RAA and CRISPR/Cas13a technology for enhanced accuracy.
- SHIELD demonstrated high sensitivity and specificity, successfully diagnosing the infection and resistance mutations in saliva samples, suggesting its potential for rapid and large-scale clinical application.
