Publications by authors named "Kuo-Hsiang Lu"

Objective: Ultrahigh frequencies (UHF) have been shown to selectively suppress the sensory pathway with a rapid onset and prolonged effect compared with low frequencies. Few studies have explored the feasibility of UHF electrical stimulation in treating overactive bladder. This study aimed to investigate whether bladder overactivity could be inhibited by UHF stimulation at the L6 nerve root.

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Background: Spinal cord stimulation (SCS) is an important pain treatment modality. This study hypothesized that a novel pulsed ultrahigh-frequency spinal cord stimulation (pUHF-SCS) could safely and effectively inhibit spared nerve injury-induced neuropathic pain in rats.

Methods: Epidural pUHF-SCS (± 3V, 2-Hz pulses comprising 500-kHz biphasic sinewaves) was implanted at the thoracic vertebrae (T9 to T11).

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Article Synopsis
  • The study examined the effects of pulsed radiofrequency (PRF) on spasticity and locomotion in rats with spinal cord injury and spasticity, comparing results with a sham operation group.
  • Results indicated that PRF effectively reduced muscle tension from spasticity but also led to a temporary decline in locomotive function, as measured by BBB scores.
  • The findings suggest that while PRF can suppress spasticity, it may negatively impact movement, highlighting the need for careful consideration of its use in treating patients with mobility issues.
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