The three-phase-lag model of heat conduction has been proposed for considering thermoelastic effect in medium. The bioheat transfer equations based on Taylor's series approximation of the three-phase-lag model were derived in conjunction with a modified energy conservation equation. For exploring the effect of non-linear expansion in the phase lag times, the Taylor's series of second-order expansion was applied.
View Article and Find Full Text PDFAppropriate heating of the tumor can ablate tumor cells with minimal damage to healthy tissue and low side effects to the patient. Therefore, it is important to estimate power dissipation requirement and predict thermal damage in tumor before hyperthermia treatment. This work applied a mathematical model on heat transfer in two-layered spherical tissue to predict the temperature profile within hyperthermia domain.
View Article and Find Full Text PDFComput Methods Biomech Biomed Engin
October 2020
A solid multi-layered concentric sphere with Gaussian space source is considered as the tissue model for magnetic hyperthermia treatment. The generalized dual-phase-lag model of bioheat transfer is used to describe the behavior of heat transport in tissue in the hyperthermia treatment process for accounting the local non-equilibrium effect. The effects of blood perfusion with the transient temperature are included in the tissue model.
View Article and Find Full Text PDFThe deep inspiration breath-hold (DIBH) technique has been utilized to reduce the cardiac dose in left-sided breast cancer (BC) patients undergoing radiotherapy. Further investigation of the parameters for selecting which patients will benefit most from DIBH is essential. We performed dosimetric comparisons for 21 patients with left-sided BC who had both computed tomography (CT)-based free-breathing (FB) and DIBH plans.
View Article and Find Full Text PDFJ Therm Biol
December 2019
Control of the therapeutic temperature is essential in performing magnetic fluid hyperthermia. Thus, reliable predictions of the power dissipation are required to determine the correct dosage of magnetic particles to be injected into the cancerous tissue prior to treatment. To meet this requirement, the present study evaluates the power dissipation requirement for two magnetic hyperthermia problems reported in the literature.
View Article and Find Full Text PDFThis paper attempts to describe the heat conduction in tissue using the dual-phase-lag mode. Evaluating the thermo-physical parameters is one of the ways to certify the thermal behavior. As a result, the paper simultaneously and inversely estimates the values of τ, τ and α for bologna based on the dual-phase-lag mode with the measurement data in the literature.
View Article and Find Full Text PDFObjective: We investigated salivary function using quantitative scintigraphy and sought to identify functional correlations between parotid dose and quality of life (QoL) for head and neck cancer (HNC) patients receiving intensity-modulated radiotherapy (IMRT).
Materials And Methods: Between August, 2007 and June, 2008, 31 patients treated IMRT for HNC were enrolled in this prospective study. Salivary excretion function (SEF) was previously measured by salivary scintigraphy at annual intervals for 2 years after IMRT.
Background: To assess the factors affecting the incidence of radiation-induced dermatitis in breast cancer patients treated with adjuvant 3 D conformal radiotherapy by the analysis of dosimetry and topical treatments.
Methods: Between September 2002 and July 2009, 158 breast cancer patients were treated with adjuvant 3 D conformal radiotherapy after undergoing surgery. Before November 2006, 90 patients were subjected to therapeutic skin care group and topical corticosteroid therapy was used for acute radiation dermatitis.
The TLD-100 readout system was optimized for various radiotherapy beam doses using the Taguchi method. The radiotherapy beam was produced by a Varian 21EX linear accelerator (LINAC) at 6MV. The beam doses were 50, 100 and 150cGy, and the measured data in each group were averaged from three TLD-100 chips.
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