Strangulation ileus caused by malposition of the ureter.

Ileus is one of the most severe diagnoses of the group of acute abdomen events. Some patients with certain forms of bowel obstruction respond well to conservative therapy. However, the diagnosis of strangulation ileus can be delayed in some situations, resulting in high morbidity and mortality in such cases.

Different cardiac loading conditions and haemodynamic monitoring in animal models.

Objective: To develop models of various cardiac loading conditions in an experimental study.

Materials And Methods: A total of 78 piglets, average weight 24 kg were divided into 4 groups under different cardiac loading conditions: Group A were spontaneously breathing pigs without haemodynamic changes, Group B were ventilated animals with increased left ventricular afterload, Group C ventilated with increased right ventricular preload and Group D ventilated with increased afterload of both heart ventricles. Haemodynamic parameters were invasively measured at 60 and 120 minutes.

[Mucinous adenocarcinoma of the appendix--case report].

The authors are describing a case of a patient with the diagnosis of the appendicular cancer. The 66-year-old patient underwent appendectomy because of signs of acute appendicitis, and than in the next step right-sided hemicolectomy because of histological finding of the mucinous adenocarcinoma of the appendix. Mucinous adenocarcinoma is the most common type of appendicular cancer, none the less this diagnosis is very rare.

Comparison of Doppler flow Tei-indexes with pulmonary artery thermodilution measurement of cardiac output in an experimental porcine model.

The objective of our study was to compare Doppler echocardiography imaging with pulmonary artery thermodilution measurement during mechanical ventilation. Total 78 piglets (6 weeks old, average weight 24 kg, under general anesthesia) were divided into 4 groups under different cardiac loading conditions (at rest, with increased left ventricular afterload, with increased right ventricular preload, and with increased afterload of both heart ventricles). At 60 and 120 min the animals were examined by echocardiography and simultaneously pulmonary artery thermodilution was used to measure cardiac output.

[Procedures on internal carotid performed under locoregional anesthesia in the Plzen Surgical Clinic, over a seven-year period. A discussion on AHA and ESVS guidelines].

During a seven-year period (2002-2008), 830 patients underwent internal carotid surgery in the Plzen Surgical Clinic. The mean age of the patients was 68 y.o.

Diffuse alveolar damage due to inappropriate strategy of mechanical ventilation in an experimental porcine model.

Background: The aim of the study was to determine how tidal volumes may affect the lung and haemodynamics during mechanical ventilation.

Materials And Methods: With the approval of the Ethics Committee, the study included a total of 24 healthy piglets, average weight 30 kg (range 28-33 kg). The animals were ventilated for 90 minutes under general anaesthesia with two different tidal volume strategies and allocated into three groups.

[Abdominal aortic aneurysms--long-term treatment results].

Objective: To evaluate the single center experience in the treatment of patients with AAA.

Methods: 586 patients undergoing open resection (OR) and EVAR (2000-2009). The average age was 72.

Ischemia-reperfusion injury in kidney transplantation from non-heart-beating donor--do antioxidants or antiinflammatory drugs play any role?

Background: Ischemia reperfusion injury (IRI) is a serious problem of transplanted kidneys from a non-heart-beating donor (NHBD). IRI is probably the main cause of primary disfunction or delayed graft function. The aim of this study was to demonstrate the reduction of IRI by intravenous application of antioxidants or immunosuppressives to the recipient before the kidney transplantation in an experimental model.

[Ischemia-reperfusion injury in kidney transplantation from non-heart beating donor--do antioxidants or antiinflammatory drugs play any role?].

Background: Ischemia reperfusion injury (IRI) represents a serious problem of transplanted kidneys from a non-heart-beating donor (NHBD). It is probably the main cause of primary a function or delayed graft function. The aim of the experimental study was to demonstrate on an experimental model the possibilities of reduction of IRI by intravenous application of antioxidants or immunosuppressives to the recipient before the kidney transplantation.

[Management of unstable pelvic fracture in the acute phase (pelvic damage control surgery)].

Pelvic fractures are serious injuries. For the diagnosis and treatment of unstable pelvic ring fracture in a haemodynamically unstable patient, it is necessary to use standard procedures with the objective to stabilise both blood circulation and the pelvic ring. According to the state of the patient, the choice is between life-saving surgery, damage control surgery and procedures of early or delayed stabilisation of the pelvic ring.

Internal carotid artery surgery in regional anesthesia at the Clinic of Surgery in Pilsen during the past 5 years.

A low percentage of perioperative complications and excellent long-term outcome following carotid artery surgery in Vascular Centers demonstrate the priority of surgical solutions in patients with significant findings on carotid arteries, in the prevention and treatment of ischemic cerebrovascular accidents. The group of patients from the Clinic of Surgery in Pilsen demonstrates the benefits of regional anesthesia during internal carotid artery surgery, both in terms of the patients' health and the financial costs incurred by the hospital.

Hybrid procedures in the treatment of pseudoaneurysms of the aortic arch--case report.

Classical surgical therapy of dilatation disorders of the aortic arch require extracorporeal circulation, selective brain perfusion and/or deep hypothermia and it is still associated with very high mortality and morbidity. Endovascular therapy has until recently indicated only been in cases when the disease did not affect the area of the origins of the main branches within the aortic arch. We are presenting a case report of a 68 year female patient with a vascular anomaly (arteria lusoria) and 2 pseudoaneurysms of the aortic arch between the origins of arteria carotis communis on the right and arteria carotis communis on the left, respectively between a.

Optimization of the model of abdominal aortic aneurysm--experiment in an animal model.

Background: Many studies have been performed in order to model abdominal aortic aneurysm (AAA) in an experimental animal, most commonly in small laboratory animals. In our study, we tried to find the best AAA model in a pig by using various mechanical and enzymatic mechanisms.

Methods: Twenty-two pigs were operated on.

[Management of the lienal artery aneurysms in the Plzen Surgical Clinic during 2002-2007].

The authors present their experience with the management of the lienal artery aneurysms. Individual types of aneurysms are presented according to their pathogenesis. Furthermore, the diagnostic options, indication criteria and treatment options are discussed.

Adverse effects of the high tidal volume during mechanical ventilation of normal lung in pigs.

Introduction: The "open lung concept" theory of mechanical ventilation is correct, but an unsuitable setting of the machine is not appropriate in children.

Type Of Study: This experimental study is a comparative, closed, randomized, double-blind study. The aim of the study was to verify the hypothesis that even a short-term high tidal volume during the course of mechanical ventilation damages the lung parenchyma as well as extra-pulmonary organs.

Does the administration of antioxidants as scavengers of reactive oxygen species in kidney transplantation really have sense?

Background: The aim of the study was to evaluate the degree of ischemia reperfusion syndrome (IRS) in serious ischemic insult of a kidney transplant and to try to mitigate the production of reactive oxygen substances (ROS) and inflammatory response.

Methods: The study was performed on 14 white pigs (20 kg). The pigs were divided in couples using a negative cross-matching and the couples were divided into the two groups.

[The ruputured abdominal aortic aneurysm--a multifactorial study].

Aim Of The Study: We examined the outcome of patients with ruptured abdominal aortic aneurysm and analysed factors that were responsible for the mortality.

Patients And Methods: From January 1 (st), 1999 to March 1 (st), 2005 82 patients with ruptured abdominal aortic aneurysm were registered in the University Hospital of Pilsen. 61 men, 21 women entered the hospital, the average age of the patients ranged to 73.

Primary cutaneous histiocyte and neutrophil-rich CD30+ and CD56+ anaplastic large-cell lymphoma with prominent angioinvasion and nerve involvement in the forehead and scalp of an immunocompetent woman.

Background: Cutaneous lymphomas co-expressing CD56 and CD30 are very rare. They share a clinicopathological overlap with natural killer- (NK)/T-cell lymphomas and anaplastic large-cell lymphomas (ALCLs), two entities with widely disparate clinical behavior.

Methods: We present a case of an immunocompetent 57-year-old Caucasian woman with a rapidly growing, angiodestructive and neuroinvasive primary cutaneous ALCL (PCALCL).

[Giant bilateral adrenal myelolipoma associated with congenital adrenal hyperplasia].

Background: Myelolipoma is a rare benign tumor formed by mature fat tissue with strata of haematopoiesis. It is mainly asymptomatic, only large myelolipomas manifest themselves by abdominal discomfort, bleeding or by symptoms of oppressing adjacent organs. It is usually localized in the region of the adrenal gland.

[An inflammatory aneurysm of the abdominal aorta].

Inflammatory aneurysm of the abdominal aorta is a rare disorder, affecting approximately 3-10% of the population with a diagnosis of the abdominal aortic aneurysm. The principal etiological agents of the disorder include bacterial microorganisms, primarily Salmonella, Staphylococcus aureus, and Escherichia coli. However, in many cases the etiology od the disorder remains unclear and, likely, autoimmune and genetic dispositions may play a certain role, as well.

Immunosuppresive agents have an influence on ischemia-reperfusion injury in kidneys procured from a non-heart-beating donor: experimental study.

Ischemic-reperfusion injury (IRI) has a considerable influence on the function of kidneys from non-heart-beating donors (NHBD) after transplantation. IRI is accompanied by a marked inflammatory reaction with the production of reactive oxygen species and of the proinflammatory cytokine tumor necrosis factor alpha. The effect on the development of ischemic-reperfusion injury of early treatment of the donor with mycophenolate mofetil and tacrolimus was monitored in an animal model of a NHBD.

[Various types of pelvic lymphadenectomy--surgical options--comparison of their significance].

Based on recent literature data, the authors summarize contemporary trends in the surgical therapy for carcinomas in the pelvic region, in particular a significance of the pelvic lymphadenectomy, which has become a standard part of the treatment of the above mentioned disorders. Furthermore, they bring forward new trends in research on lymphatic mapping and the sentinel lymphonode detection.

Can ischemia-reperfusion syndrome in transplanted kidneys procured from non-heart-beating donors be influenced by adding selenium into the reperfusion solution? An experimental study.

Ischemia-reperfusion syndrome significantly influences the function of a kidney transplanted from a non-heart-beating donor (NHBD). An animal model of NHBD was used to monitor the influence of the exogenous addition of selenium in the perfusion solution (HTK, Custodiol) on the generation of free oxygen radicals between 0 and 120 minutes after transplantation of the NHBD organ. During this interval, the malondialdehyde concentration, an indicator of free oxygen radicals in the venous blood of the transplanted kidney, significantly decreased.