Publications by authors named "Kunrong Liu"
A bibliometric analysis of non-coding RNA studies in acute pancreatitis.
Medicine (Baltimore)
March 2024
Article Synopsis
- The study focuses on the role of non-coding RNA (ncRNA) in acute pancreatitis, highlighting its importance in disease onset, progression, and therapy.
- A bibliometric analysis was conducted using data from 2000-2023, revealing 563 publications mainly from China and identifying key research themes such as inflammation, microRNA expression in pancreatic cancer, and ncRNA as diagnostic markers.
- The findings indicate that ncRNA research is well-established and provide insights for future studies, suggesting potential research directions based on emerging hotspots like injury pathways and extracellular vesicles.
Article Synopsis
- Safer and more effective treatments for acute pancreatitis (AP) are needed, and Qingjie Huagong decoction (QJHGD) has shown promising clinical effects but its mechanisms were unclear.
- The study aimed to explore how QJHGD influences AP both in cell cultures and in mouse models, using various biochemical and molecular techniques to analyze its effects.
- Results indicated that QJHGD enhances cell viability and reduces pancreatic injury by regulating a specific pathway involving circHipk3, miR-193a-5p, and NLRP3, which highlights a new mechanism for its therapeutic action against AP.