Publications by authors named "Kunqian He"
In vitro modeling of recurrent Dermatofibrosarcoma Protuberans: Assessment of 5-aminolevulinic acid photodynamic therapy efficacy.
Photodiagnosis Photodyn Ther
June 2024
Background: Dermatofibrosarcoma Protuberans (DFSP) is a rare, low-grade malignant tumor of the dermis with a high recurrence rate post-surgery. Current treatments, including surgery, radiotherapy, and targeted therapy, have limitations. Photodynamic therapy (PDT) with 5-aminolevulinic acid (5-ALA) is a promising non-invasive approach, but its efficacy in DFSP treatment remains underexplored.
View Article and Find Full Text PDFLow selectivity and tumor drug resistance are the main hinderances to conventional radiotherapy and chemotherapy against tumor. Ion interference therapy is an innovative anti-tumor strategy that has been recently reported to induce metabolic disorders and inhibit proliferation of tumor cells by reordering bioactive ions within the tumor cells. Calcium cation (Ca) are indispensable for all physiological activities of cells.
View Article and Find Full Text PDFEfficacy and safety of fractional carbon dioxide laser followed by 5-aminolevulinic acid photodynamic therapy for keloids.
Photodiagnosis Photodyn Ther
February 2024
Article Synopsis
- - Keloids are tough scars that can cause both physical and cosmetic issues, and a study evaluated the combination of fractional CO laser and photodynamic therapy (PDT) using 5-aminolevulinic acid (ALA) for treatment efficacy.
- - In the study with 12 patients, this combined treatment showed a significant reduction in scar severity and related symptoms like pain and itching, with patients reporting high satisfaction despite some minor side effects like hyperpigmentation.
- - The findings suggest that this method is effective for keloid treatment but call for further research with larger groups to confirm the treatment's benefits and safety.