Toxic effects of chronic occupational mercury vapor exposure on female workers of childbearing age.

Background: Few studies have been conducted on women of childbearing age with chronic mercury poisoning caused by mercury vapor exposure.

Methods: Occupational exposure, clinical symptoms and signs, laboratory tests, auxiliary examinations, treatment, and follow-up of 31 female workers with chronic mercury poisoning from a mercury thermometer processing factory who received inpatient treatment at our hospital between September 2021 and August 2022 were analyzed.

Results: In 31 female workers of childbearing age (23-43 years) who were chronically exposed to mercury vapor (3-31 months), urinary mercury levels exceeded the normal range.

Early prognosis prediction for non-variceal upper gastrointestinal bleeding in the intensive care unit: based on interpretable machine learning.

Introduction: This study aims to construct a mortality prediction model for patients with non-variceal upper gastrointestinal bleeding (NVUGIB) in the intensive care unit (ICU), employing advanced machine learning algorithms. The goal is to identify high-risk populations early, contributing to a deeper understanding of patients with NVUGIB in the ICU.

Methods: We extracted NVUGIB data from the Medical Information Mart for Intensive Care IV (MIMIC-IV, v.

Silica nanoparticles induce pulmonary damage in rats via VEGFC/D-VEGFR3 signaling-mediated lymphangiogenesis and remodeling.

Silica nanoparticles (SiNPs) are widely used as drug carriers for improving drug delivery and retention. The lungs are highly sensitive to the toxicity of SiNPs entering the respiratory tract. Furthermore, pulmonary lymphangiogenesis, which is the growth of lymphatic vessels observed during multiple pulmonary diseases, plays a vital role in promoting the lymphatic transport of silica in the lungs.