YQFM alleviated cardiac hypertrophy by apoptosis inhibition and autophagy regulation via PIK/AKT/mTOR pathway.

Ethnopharmacological Relevance: As a traditional compound preparation of Chinese medicine, Yiqi Fumai lyophilized injection (YQFM) has protective effects on various cardiac diseases including cardiac hypertrophy, which is the primary cause of arrhythmia. However, the involved mechanism remains unclear.

Aim Of The Study: This study was projected to investigate whether YQFM could prevent cardiac hypertrophy and arrhythmia concurrence.