Publications by authors named "Kunj Jain"
Objective: To examine the factors influencing urologists' decision to offer slings instead of AUS for managing male stress urinary incontinence.
Methods: The American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database 2006-2021 was used to identify patients undergoing surgical procedures for male urinary incontinence using current procedural terminology (CPT) codes. The Current procedural terminology (CPT) codes for AUS (53,445) and male slings (53,440) were used to analyze the data appropriately.
Purpose: This study aimed to investigate the long-term outcomes of non-operative, operative, and minimally invasive surgery management of high-grade renal injuries (Grades III-V) in an underserved population at a high-volume trauma center.
Methods: We conducted a retrospective chart review of 93 patients who sustained high-grade renal trauma and presented to University Hospital, a Level 1 trauma center, between 2017 and 2022. The patients were categorized by initial management strategy: non-operative, operative, or minimally invasive surgery (endoscopic urologic and interventional radiologic procedures).
Background: We analyzed trends in age at surgery and surgical approach over time and geography.
Methods: We performed a systematic review according to PRISMA-IPD guidelines to include individual patient data. Collected data included age at surgery, location of surgery, and surgical approach.
Purpose: Surgical resident autonomy in procedures has been eroding over time, due to multiple factors that include duty hour restrictions, focus on operating time, complication rate, and trust among supervising physicians. This study examines whether urology residents at the Veterans Affairs hospitals (VA) have experienced decreased surgical autonomy and contributing factors.
Methods: The national VA Surgical Quality Improvement Program (VASQIP) was queried for the most common urologic procedures between 2004 to 2019 with resident involvement.
Introduction: Panurethral strictures represent the most severe form within the anterior urethral stricture spectrum, requiring more technically complex repairs and resulting in poorer outcomes compared to localized anterior urethral strictures (penile or bulbar). This abstract aims to describe the distinct characteristics of patients with panurethral strictures in a low socioeconomic status population.
Methods: Patients presenting with localized anterior (penile or bulbar) or panurethral strictures at University Hospital in Newark, NJ, between 2021 and 2023 were retrospectively identified.
Objective: To review malpractice suits stemming from urethroplasty intervention, which is the standard of care for patients suffering from urethral strictures.
Methods: This retrospective study analyzed the LexisNexis and Westlaw databases between 1980 and 2024. Each database was queried with "urethroplasty" which yielded 48 cases and 20 jury verdicts/settlements in the LexisNexis database and 46 cases and 14 jury verdicts in the Westlaw database.
Objectives: In the treatment of closed intertrochanteric fractures, the two most common treatment options are intramedullary medullary nail (IMN) and dynamic hip screw (DHS), yet the best treatment method remains controversial. The purpose of this study is to determine the difference in mortality and morbidity between IMN and DHS. Secondarily, this study determines which pre-operative risk factors affect rates of morbidity and mortality.
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- Intertrochanteric hip fractures are common and can lead to complications from surgical treatments, prompting a comparison between sliding hip screw fixation (SHS) and cephalomedullary nailing (CMN).
- The study reviewed 17 articles, including data from over 3,300 patients, to investigate various complications such as nonunion, infection, and refracture rates.
- Results indicated that SHS has significantly lower rates of refractures and reoperations compared to CMN, but no major differences were found in other complication rates, suggesting the need for further research as surgical techniques evolve.*
Purpose Of Review: The purpose of this review is to investigate the current use and effectiveness of active surveillance (AS) for clinical low-risk prostate cancer (PCa) in men considered to be "high-risk" based on the factors of race, genetics, healthcare access, and socioeconomic status.
Recent Findings: Advances in molecular biomarkers and imaging have improved the detection, risk stratification, and treatment of PCa. Still, overdiagnosis and overtreatment of indolent disease remain a concern.
Background: Debate over the optimal age at time of surgery for treatment of brachial plexus birth injury (BPBI) remains controversial, and there exists geographical varia- tion in surgical preference for age at time of surgery. The objective of this review was to analyze trends in age and geography in brachial plexus microsurgery for treatment of brachial plexus birth injury (BPBI) over time.
Methods: Review of the literature in this study was con- ducted according to the Preferred Reporting Items for Sys- tematic Reviews and Meta-Analysis (PRISMA) guidelines.
Purpose: The prevalence of erectile dysfunction (ED) and the utilization of inflatable penile prosthesis (IPP) among prostate cancer patients are understudied. The aim of the study was to examine the relationships between ED, prostate cancer treatment type and IPP implantation in a national cohort.
Materials And Methods: We identified a retrospective cohort of Surveillance, Epidemiology, and End Results (SEER)-Medicare patients diagnosed with locoregional prostate cancer between 2006 and 2011 and treated with surgery or radiation.
Article Synopsis
- - The study investigates how the age of pediatric patients at the time of upper trunk brachial plexus microsurgery affects surgical outcomes, specifically focusing on neonatal brachial plexus palsy (NBPP).
- - A systematic review of literature identified 25 relevant papers, revealing a significant negative correlation between older age at surgery and poorer hand-to-mouth function based on the Mallet subscore.
- - Results indicate that delaying surgery past 6-9 months significantly impacts recovery, suggesting earlier intervention may improve outcomes for hand-to-mouth capability in affected infants.
Carbon-Fibre-Reinforced Polymers (CFRPs) have seen a steady rise in modern industrial applications due to their high strength-to-weight ratio and corrosion resistance. However, their potential is being hindered by delamination which is induced on them during machining operations. This has led to the adoption of new and innovative techniques like cryogenic-assisted machining which could potentially help reduce delamination.
View Article and Find Full Text PDFProtein prenylation is believed to be catalyzed by three heterodimeric enzymes: FTase, GGTase1 and GGTase2. Here we report the identification of a previously unknown human prenyltransferase complex consisting of an orphan prenyltransferase α-subunit, PTAR1, and the catalytic β-subunit of GGTase2, RabGGTB. This enzyme, which we named GGTase3, geranylgeranylates FBXL2 to allow its localization at cell membranes, where this ubiquitin ligase mediates the polyubiquitylation of membrane-anchored proteins.
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