[Changes in the type and frequency of chromosome associations in human peripheral blood lymphocytes after treatment with colcemid].

Changes in the character and frequency of chromosome associations in metaphase cells of human lymphocyte cultures during colcemid treatment were studied. As the time of colcemid treatment was extended from 0 to 24 h, the number of both cells with chromosome associations and of chromosomes involved in this process was seen to increase. After a 1 h incubation of cells with colcemid the number of nucleolar-organizing chromosome associations increased considerably.