Publications by authors named "Kunio Yoshizawa"

This study aimed to examine the relationship between computed tomography (CT) values of the condylar surface in the coronal plane, condylar morphology and the disc positions in the temporomandibular joint (TMJs) in patients with deformities before and after orthognathic surgery.  MATERIALS AND METHODS: The maximum CT values (pixel values) on the condylar surface, condylar thickness, condylar width, condylar angle, condylar height, and joint space were measured. TMJ disc position was classified into five types (anterior type, fully covered type, posterior type, anterior disc displacement with [AW] and without reduction [AWO]), using magnetic resonance imaging (MRI), before and 1 year after surgery.

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Article Synopsis
  • Pyogenic spondylodiscitis is an infectious spinal disease that leads to serious mobility issues, making its diagnosis tricky due to rapid onset and vague symptoms.
  • A 79-year-old man with diabetes developed severe abdominal pain and paraplegia after oral surgery, and tests confirmed he had pyogenic spondylodiscitis and an infection caused by methicillin-sensitive Staphylococcus aureus.
  • Although the infection was effectively treated and his respiratory issues improved, the patient remained paralyzed in his lower body, later rehabilitating to a point where he could walk with assistance.
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  • This paper presents a new reconstructive technique using a transorally inserted Cosmofix fixation plate, which is less invasive and more aesthetic.
  • It describes two cases of stage 3 medication-related osteonecrosis of the jaw (MRONJ) where a segmental mandibulectomy was performed, followed by successful reconstruction.
  • The new method shows promising results with good occlusion and no aesthetic issues after over a year, making it suitable for high-risk patients, unlike traditional surgeries that involve facial incisions.
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This study aimed to evaluate maxillary bone healing and computed tomography (CT) values after Le Fort I osteotomy with sagittal split ramus osteotomy in patients with class II and III malocclusion. Four absorbable plates and screws were used to fix the maxillary segments in all patients. For 112 sides (58 patients), the bone defect areas at the anterior and posterior sites between the maxillary segments were measured using 3-dimensional CT views reconstructed over a constant CT value at 1 week and 1 year postoperatively.

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Alveolar bone quality at the implantation site affects the initial stability of dental implant treatment. However, the relationship between bone quality and osseointegration has yet to be evaluated. Herein, we aimed to investigate the effect of bone quality on dental implant stability in osseointegration formation changes.

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This report describes a rare case of a foreign body in the sphenoid sinus from the tip of an osteotome, which was lodged during the Le Fort I osteotomy. After surgery, a 2-mm-diameter round-shaped foreign body was seen as an opaque image in the right sphenoid sinus on computed tomography. The tip of the broken osteotome (Bauer) was confirmed after the intraoperative instruments were investigated.

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The purpose of this study was to quantitatively compare changes in tongue pressure and lip closing force among skeletal Class II and Class III patients, who had undergone orthognathic surgery, and a control group. Maximum tongue pressure and lip closing forces were measured preoperatively and at 6 and 12 months postoperatively. Time-course changes were analyzed and compared among the groups.

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This study aimed to compare the bone healing and stability of the chin with a pre-bent absorbable plate and a manually bent absorbable plate after advancement genioplasty. Patients with class II malocclusion who underwent genioplasty with bimaxillary surgery were included. After genioplasty, two absorbable bicortical screws were fixed on both sides.

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Objectives: This study aimed to examine the relationship between condylar surface computed tomography (CT) values in the coronal plane and condylar morphology in patients with jaw deformities classes II and III before and after orthognathic surgery.

Materials And Methods: The maximum CT values (pixel values) at three points on the condylar surface, height, and joint space were measured on the coronal plane. The condylar width, thickness, and angle were measured on the horizontal plane preoperatively and at 1 year postoperatively.

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Rationale: Infections that spread to the pterygomandibular muscle can be misdiagnosed as temporomandibular disorder (TMD) because of the resulting difficulty in opening the mouth. Importantly, infection of the pterygomandibular space can extend to the skull base in the early stages, and a delay in therapeutic intervention can lead to severe complications.

Patient Concerns: A 77-year-old Japanese man with trismus after pulpectomy was referred to our department.

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Purpose: This study aimed to assess the correlation between temporomandibular joint (TMJ) disc position and skeletal stability and identify the cephalometric measurements associated with relapse after bimaxillary surgery.

Methods: The participants were 62 women with jaw deformities (124 joints) who underwent bimaxillary surgery. The TMJ disc position was classified into four types (anterior disc displacement (ADD), anterior, fully covered, and posterior) using magnetic resonance imaging, and cephalometric analysis was performed preoperatively and 1 week and 1 year postoperatively.

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This retrospective study aimed to evaluate the efficacy of support splint treatment for deformities and deviations of the nasal septum after Le Fort I osteotomy (LFI). Patients were divided into two groups: the retainer group wore a nasal support splint immediately after LFI for 7 days, and the no retainer group did not wear a nasal support splint. Evaluation was performed by measuring the ratio of the difference between the left and right sides of the nasal cavity area (ratio of nasal cavity) and the angle of the nasal septum using three computed tomography frontal images (anterior, middle, and posterior) before and one year postoperatively.

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Article Synopsis
  • - The study focused on how the CT values of the ramus bone change after sagittal split ramus osteotomy (SSRO) in patients with class II and class III jaw deformities using absorbable plates and screws.
  • - Researchers analyzed CT values of 57 female patients preoperatively and one year post-surgery, measuring at specific levels of the bone to assess changes in density.
  • - Results indicated overall decreases in CT values at most sites but increases in specific areas for class II and class III patients, suggesting differing impacts on bone quality based on surgical type.
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Rationale: Nodular fasciitis (NF) can be misdiagnosed as a sarcoma because of its rapid growth and pathological features, such as nuclear atypia and mitoses.

Patient Concerns: We present a rare case of a 72-year-old Japanese man who developed NF with suspected postirradiation myxofibrosarcoma (MFS) after segmentectomy for left-sided osteoradionecrosis (ORN) of the mandible.

Diagnosis: A mass appeared in the intraoral postoperative wound 1 year after left-sided mandibular segmentectomy and showed rapid growth, reaching a size of 50 mm within 2 months.

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Sex determination is a crucial factor in the identification of unidentified human remains. Sex determination by DNA analysis is particularly useful because it can be applied to samples for which morphological characteristics are unavailable. Because samples handled in forensic DNA typing are easily degraded by environmental factors and microorganisms, there is a need for a method that can accurately determine sex even in highly decayed samples.

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Purpose: This study aimed to evaluate and predict the factors that affect the postoperative maxillary sinus and inferior nasal cavity conditions after Le Fort I osteotomy.

Subjects And Methods: The rate of aerated (healthy) sinus area and the inferior nasal airway area were calculated by preoperative computed tomography measurements and at 1 week and 1 year postoperatively. Factors predicting the rate of aerated sinus area and the ratio of the inferior nasal cavity area after 1-week were examined using these variables.

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Objective: This study aimed to evaluate intercellular bridges in the depth of invasion (DOI) measurement area as prognostic factors in oral squamous cell carcinoma (OSCC).

Study Design: The mode of invasion was determined based on the Yamamoto-Kohama classification system by observing the hematoxylin-eosin-stained whole-slide images of specimens obtained from 78 patients with OSCC, and the clinicopathologic features were characterized. The presence of intercellular bridges was analyzed in 46 patients with Yamamoto-Kohama classification grade ≥3 whose DOI was measured by dividing the measurement area into 3 parts: the surface, center, and front of the tumor.

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The epithelial-mesenchymal transition (EMT) is a crucial morphological event that occurs during epithelial tumor progression. Snail and ZEB1/2 (ZEB1 and ZEB2), known as EMT transcription factors, are key regulators of this transition. ZEB1/2 are positively correlated with EMT phenotypes and the aggressiveness of cancers.

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Background: The purpose of this study was to evaluate the association between the immunohistochemistry (IHC) of protein tyrosine kinase 7 (PTK7) expression and clinicopathological factors of oral squamous cell carcinoma (OSCC).

Methods: Tissue specimens were obtained from 80 patients with primary OSCC. IHC scoring was conducted according to the rate of positive cell and staining intensity.

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Objective: The Yamamoto-Kohama criteria are clinically useful for determining the mode of tumor invasion, especially in Japan. However, this evaluation method is based on subjective visual findings and has led to significant differences in determinations between evaluators and facilities. In this retrospective study, we aimed to develop an automatic method of determining the mode of invasion based on the processing of digital medical images.

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Background: Bisphosphonates are frequently used for osteoporosis. Medication-related osteonecrosis of the jaw, a complication of bone-modifying agents, including bisphosphonates or angiogenic inhibitors, can be challenging to treat in elderly patients with numerous preexisting conditions. Achieving good treatment outcomes is especially difficult in patients with pathological fractures accompanied with extraoral fistulae.

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The aim of the study was to examine lateral pterygoid muscle (LPM) and temporomandibular joint (TMJ) disc before and after Le Fort I osteotomy with and without intentional pterygoid plate fracture and sagittal split ramus osteotomy (SSRO) in class II and class III patients. Le Fort I osteotomy and SSRO were performed in class II and class III patients. LPM measurements using oblique sagittal computed tomography (CT) images and TMJ disc position using magnetic resonance imaging (MRI) were examined.

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The present report describes a case series in which spacers with boluses were used at various sites in the oral cavity to enhance the therapeutic effect of radiation therapy in oral squamous cell carcinoma. In radiotherapy, the surface dose is reduced due to the build-up region of X-rays. In the present study, a bolus was used to complement the build-up region and increase the surface dose effect.

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Objective: This study aimed to assess mandibular morphologic changes to the condyle, ramus, mandibular body, and inferior mandibular border defect after sagittal split ramus osteotomy in class II and III patients.

Study Design: The relationships among the condyle, ramus, and mandibular body measured by computed tomography preoperatively and postoperatively were assessed and factors related to the reduction of the condylar square and mandibular inferior border defect were examined.

Results: Patients included 72 female patients with jaw deformity (36 skeletal class II cases, 36 skeletal class III cases).

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