[Resection under Endoscopic Guidance of Papillary Fibroelastoma in the Left Ventricular Outflow Tract:Report of a Case].

A 76-year-old man was admitted to our hospital for a thorough examination of a suspected cardiac tumor on transthoracic echocardiography. Transesophageal echocardiography demonstrated a 9.4×8.

Extrapulmonary pneumocystosis in an antiretroviral therapy-naïve, HIV-positive patient.

Pneumocystis jirovecii is a common opportunistic fungal pathogen that commonly affects immunocompromised individuals and can cause P. jirovecii pneumonia. Extrapulmonary P.

A case report of SARS-CoV-2 confirmed in saliva specimens up to 37 days after onset: Proposal of saliva specimens for COVID-19 diagnosis and virus monitoring.

We present the case of a 71-year-old man who, despite becoming asymptomatic after having some mild symptoms of COVID-19, had SARS-CoV-2 RNA detected for 37 days after onset, from his concentrated and purified saliva specimens using sugar chain-immobilized gold nanoparticles. It was suggested that the early morning saliva specimens were more likely to show positive results than those obtained later in the day.

Three-year prospective, observational study of central line-associated bloodstream infections in a 600-bed Japanese acute care hospital.

Background: Central line-associated bloodstream infection (CLABSI) is an important concern associated with central venous catheter (CVC) use. The objective of this study was to determine the influences of CVC access sites, CVC types, and presumed causative microorganisms on CLABSI occurrence in an acute care hospital.

Methods: We conducted a prospective, observational study of CLABSI occurrence for 3 consecutive years in a 600-bed Japanese acute care hospital.

[Other viral food poisoning (hepatitis A and E)].

Hepatitis A and E viruses are spread via the fecal-oral route. In the endemic area, restaurant and school outbreaks due to contaminated water or food have been reported. The clinical signs and symptoms in patients with typical hepatitis A and E are similar to those seen with other forms of acute viral hepatitis.

[Infection control in Hamamatsu Medical Center].

Since the department of Infection Control was established in Hamamatsu Medical Center, a 615-bed community teaching hospital, we have been practicing infection control program including surveillance, coping with needle stick injuries, introducing Interlink system, PPD testing and influenza vaccination to the health care workers. One of the obstacles in the practice of the hospital infection has been a cost, and the infection control does not progress as long as this can't be solved. The infection control, which we have been carrying out so far, seems to have a lot of unnecessary practices.

[Long-term complete remission following allogeneic PBSCT in a case of relapsed lymphoblastic lymphoma after BMT from the same donor].

An 18-year-old man was diagnosed as having lymphoblastic lymphoma in January 1997, and treated with chemotherapy. At the 1st relapse, bone marrow transplantation from HLA-identical sibling was performed in June 1998 with only acute graft-versus-host disease (GVHD). At the 2nd relapse, peripheral blood stem cell transplantation from the same donor was performed in October 2000 with both acute and chronic GVHD, which has continued for 25 months, and complete remission has also been maintained.

[A case of chronic myelogenous leukemia responding to imatinib mesilate (Glivec) after relapse of blastic crisis following allogeneic bone marrow transplantation].

We report a patient with chronic myelogenous leukemia that responded to imatinib mesilate after relapse of blastic crisis following allogeneic bone marrow transplantation. The patient received an unrelated bone marrow transplantation in the 3rd chronic phase, after which the 3rd blastic crisis occurred 5 months later. Since the case was refractory to chemotherapy at that time, imatinib mesilate (600 mg/day) was given, which resulted in a complete cytogenetical remission (CCR).

[Infection prevention and safe practice (referring to CDC guideline)].

Recent nosocomial infections, such as HCV and tuberculosis, have stimulated interest in infection control practices in health care setting. Therefore, Infection Control Doctors (ICDs) have already started to make best strategies for infection prevention and safe practice. However, many obstacles lie ahead of them, with the cost as the most important.

Emergence of Nonalbicans Candida Species in Immunocompromised Leukemia Patients during Fluconazole Treatment.

The incidence of the emergence of nonalbicans Candida species during fluconazole treatment was surveyed in leukemia patients who were severely immunocompromised due to either intensive chemotherapy or bone marrow transplantation during the 3-year period from April 1993 to March 1996. Thirty-three patients received either prophylactic or therapeutic fluconazole administration for at least 7 days. In 7 of these 33 patients (21.

Clinical evaluation of monotherapy with cefpirome for infections complicating hematological disorders.

The clinical effects of cefpirome (CPR) monotherapy were evaluated in 38 infected patients with hematological diseases. The underlying diseases of the patients were chiefly acute leukemia, myelodysplastic syndrome, malignant lymphoma, and aplastic anemia, and 18 patients were clinically neutropenic (<500 neutrophils/μL). Septicemia, pneumonia, or an unexplained fever, were the predominant complicating infections.