Publications by authors named "Kunihide Tanaka"
Objective: To verify understanding and awareness of fertility preservation (FP) in pediatric patients undergoing FP treatments.
Methods: A questionnaire survey was conducted before and after explanation of fertility issues and FP treatments for patients 6-17 years old who visited or were hospitalized for the purpose of ovarian tissue cryopreservation (OTC) or oocyte cryopreservation (OC), or sperm cryopreservation between October 2018 and April 2022. This study was approved by the institutional review board at St.
Background: Creating obstructive uropathy (OU) during glomerulogenesis in the fetal lamb results in multicystic dysplastic kidney (MCDK) at term. We explored this using immunohistochemical techniques.
Method: OU was created in fetal lambs at 60-day gestation, ligating the urethra and urachus.
Article Synopsis
- The study investigates the adequacy of revised patient selection criteria for fertility preservation in children and adolescents, focusing on their characteristics and the consultation process at a university hospital.
- Out of 74 patients referred for consultation, more than half had hematological diseases, with 41.9% successfully undergoing ovarian tissue cryopreservation; complications were minimal.
- The results showed that most patients over 12 experienced primary ovarian insufficiency post-treatment, suggesting that while the selection criteria may be appropriate, some long-term challenges remain.
Background: In biliary atresia (BA), the ultrasonic triangular cord (TC) sign is positive at ≥ 3 mm, but sometimes there is BA even if it is ≤ 3 mm. For improving the ultrasonographic diagnosis, we have established a new evaluation, adding the ratio of the anterior/posterior thickness (TC ratio) in the hyperechoic area and the presence of a cystic lesion in the triangular cord (TCC).
Methods: We examined 24 cases of suspected BA who demonstrated acholic stools from 2006 to 2020.
Background: We created abdominal wall defects (AWD) in fetal lambs to investigate possible causes of scoliosis.
Methods: We incised the upper abdominal wall (including Rectus) in 60-day gestation fetal lambs, from the midline to either the right (Group A) or left (Group B) costal margin, in 14 lambs carried by 7 ewes. They were delivered by cesarean section at term (about 145 days).
(1) Background: Renal development involves frequent expression and loss of transcription factors, resulting in the activation of genes. Wilms' tumor 1 (WT1), hepatocyte nuclear factor-1-beta (HNF1β), and paired box genes 2 and 8 (Pax2 and Pax8) play an important role in renal development. With this in vivo study, we examined the period and location of expression of these factors in renal development.
View Article and Find Full Text PDFArticle Synopsis
- Fertility preservation for children, specifically through ovarian tissue cryopreservation (OTC), is under-researched, particularly regarding its surgical methods.
- A study analyzed 25 girls who had OTC from November 2015 to May 2020, focusing on their preoperative management and medical backgrounds, which included various health conditions like leukemia and brain tumors.
- The findings indicate that OTC can be safely performed in children, even those with severe medical issues, and that monitoring white blood cell and C-reactive protein levels post-surgery can help detect potential infections.
Background: We have reviewed the surgical procedures performed and outcomes for low-birth-weight infants with acquired subglottic stenosis.
Methods: The gestational age at birth, birth weight, age at Laryngotracheal reconstruction, and therapeutic outcome over the past 26 years were reviewed. Laryngotracheal reconstruction was initially performed by costochondral grafting involving only the anterior wall for the first operation, but since 2010 a costal cartilage was also inserted into the posterior wall of the cricoid cartilage using the BENSON pylorus spreader to split the cartilage.
Background: The standard surgical procedure for congenital biliary dilatation (CBD) consists of excision of extrahepatic bile duct and Roux-en-Y hepaticojejunostomy (HJ). However, alternative reconstructive operations for CBD includes hepaticoduodenostomy (HD). We compared postoperative complications and therapeutic outcomes of these two operations at our institution.
View Article and Find Full Text PDFBackground: We investigated the risk factors influencing ascending testis following laparoscopic percutaneous extraperitoneal closure (LPEC) for inguinal hernia or hydrocele.
Methods: Boys undergoing LPEC between 2014 and 2018 had their medical records and operative movies reviewed. Group A patients required orchiopexy after LPEC.
Purpose: We report effects of treatment for pectus excavatum (PE) with a Vacuum Bell (VB).
Materials And Methods: Fifteen patients (13 males and 2 females) undergoing VB therapy over 6 years, aged 6-17 years (mean: 11.1 years), were divided into two Groups: Group 1 (G1), preteenagers (< 13 years); Group 2 (G2), teenagers (≧ 13 years).
Background: In congenital diaphragmatic hernia (CDH), there is pulmonary hypoplasia (PH) and also pulmonary vascular and bronchial abnormalities. Few studies have investigated bronchial maldevelopment in CDH. We evaluated bronchial area (BA) by bronchography in a fetal lamb DH model to develop a measure of PH.
View Article and Find Full Text PDFBackground: The kidney develops from an intimate interaction between the ureteric bud and the metanephric mass. We attempted to differentially stain the derivatives of the ureteric bud and the metanephric mass in ovine fetuses.
Methods: After appropriate approval, 47 fetal lambs' kidneys at 50 (4), 60 (6), 70 (5), 80 (4), 100 (10), 110 (8), 145 (10) days' gestation (term is 140-145 days) were obtained.
Background: There are few reports comparing type 1 alveolar epithelial cell development with histopathological image analysis. We investigated these as indicators of maturity in fetal lambs' lungs in a congenital diaphragmatic hernia (CDH) model.
Methods: We created left CDH in 4 fetal lambs at 75 or 76days' gestation (Group A).
Background/purpose: Respiratory distress in babies with large abdominal wall defects suggests a relationship to decreased diaphragmatic movement. We evaluated pulmonary development in a fetal lamb gastroschisis model.
Methods: We created gastroschisis in 25 fetal lambs at 60days gestation (group A).
Background: There is no good prognostic indicator for biliary atresia (BA). We reviewed liver biopsies taken during the initial procedure to find a prognostic marker.
Methods: Thirty-two BA cases underwent Kasai operation from 1976 to 2009.
Background: In our fetal lamb model of lower urinary tract obstruction, a pressure limited shunt preserves bladder function and renal development. This study investigates the effects on pulmonary histology.
Methods: We created obstructive uropathy (OU) in 60-day gestation fetal lambs, ligating the urethra and urachus, and delivering them at term (130-145days).
Purpose: To clarify the predictors of post-operative complications of pediatric acute appendicitis.
Methods: The medical records of 485 patients with acute appendicitis operated on between January 2006 and November 2014 were retrospectively reviewed. Age, sex, preoperative WBC, CRP, and appendix maximum short diameter on diagnostic imaging (AMSD) were compared retrospectively with the complications group (Group C) vs the non-complication group (Group NC) by Student's T test, Fisher exact test and Multivariate analysis.
Background: In our fetal lamb model of lower urinary tract obstruction, a valved shunt preserves bladder function. This study investigates the effects on renal histology.
Methods: We created obstructive uropathy (OU) in 60-day gestation fetal lambs, ligating the urethra and urachus, and delivering them at term (130-145days).