[Stage wise treatment of uterine arteriovenous malformation complicated by recurrent haemorrhage].

Uterine arteriovenous malformation is a rarely encountered disease threatening with massive haemorrhage. The article describes a clinical case report regarding a 37-year-old woman presenting with this pathology and previously hospitalized twice with severe posthaemorrhagic complications at a 5-month interval due to refusal from timely hysterectomy. A vascular formation in the womb was detected at ultrasonography, however its pattern was identified only by computed tomography of small pelvis organs with intravenous contrasting.

[Thrombectomy for acute iliofemoral thrombosis in prevention of pulmonary embolism].

Background: Acute thrombosis in the system of the inferior vena cava is one of the most common vascular diseases and is of serious danger as a potential source of one of the most severe complications. In order to assess efficacy of open thrombectomy for embologenic iliofemoral venous thromboses we carried out comparison of the results of open thrombectomy and implantation of cava filters in a total of 119 patients presenting with iliofemoral thrombosis.

Patients And Methods: Open thrombectomy was performed in a total of 59 patients.

[Cell therapy of critical lower limb ischemia (problems and prospects)].

Critical limb ischemia is a syndrome that combines several peripheral artery diseases with different ethiology and pathogenesis but with similar prognosis, high morbidity and mortality. Possibility of surgical and conservative treatment of critical limb ischemia almost completely exhausted. Some hopes have arisen due to progress in cell technology.

Acetylated and methylated β-cyclodextrins as viable soluble supports for the synthesis of short 2′-oligodeoxyribo-nucleotides in solution.

Novel soluble supports for oligonucleotide synthesis 11a-c have been prepared by immobilizing a 5′-O-protected 3′-O-(hex-5-ynoyl)thymidine (6 or 7) to peracetylated or permethylated 6-deoxy-6-azido-β-cyclodextrins 10a or 10b by Cu(I)-promoted 1,3-dipolar cycloaddition. The applicability of the supports to oligonucleotide synthesis by the phosphoramidite strategy has been demonstrated by assembling a 3′-TTT-5′ trimer from commercially available 5′-O-(4,4′-dimethoxytrityl)thymidine 3′-phosphoramidite. To simplify the coupling cycle, the 5′-O-(4,4′-dimethoxytrityl) protecting group has been replaced with an acetal that upon acidolytic removal yields volatile products.

[D-dimer in diagnosis of acute thromboses of lower-limb deep veins].

Analysed herein is a potential role the D-dimer plays in diagnosis of acute venous thromboses of the lower limbs. The D-dimer blood plasma levels were determined in a total of 195 patients with either suspected or known acute thrombosis of the lower-limb deep veins. The D-dimer concentration was measured by the immunoturbidimetric method.

[Surgical correction of isolated coarctation of the aorta in infants of the first year of life].

Long-term results of surgical treatment of isolated coarctation of the aorta were studied in infants from the first year of life till 14 years. In infants of the first year of life elimination of coarctation of the aorta with end-to-end anastomosis is more preferable than isthmoplasty of the aorta of the left subclavian artery, since risk of recoarctation is less, the subclavian artery remains preserved, the ductal tissues are completely dissected. An important condition of success of the operation with elimination of the end-to-end CA is thought to be maximal mobilization of the aorta from the surrounding tissues which leads to greater mobility, less tension in the anastomosis zone.

[Modification of Norwood's operation in children].

Modified Norwood's operations were performed on 46 children aged from 1 to 180 days. The operations were performed on patients with the single heart ventricle in combination with hypoplasia or atresia of the aorta. Atrioseptostomy was fulfilled in 29 children.

[Transillumination-assisted phlebectomy with the help of the TriVex system in comprehensive management of varicose disease of lower-limb veins].

The present work was undertaken to evaluate a new minimally invasive method of surgical management of varicose disease by means of the TriVex unit. The method is based on transillumination of saphenous veins in an aqueous medium, which makes it possible to perform radical removal thereof form separate punctures under visual control with the help of a specially designed vein stripper. Transillumination-assisted phlebectomy (TIP) was compared with microphlebectomy (MPE) according to the Varady's technique.

[Replacement of lumbosacral intervertebral disks using artificial prostheses: surgical tactics and technique].

The mail goal of the study is to present surgical technique of intervertebral disk replacement using artificial disks and to completely evaluate effectiveness of this modality of treatment of degenerative spine disease using a set of original scales, clinical data and neuroradiological examination. Since 2002 to 2007 14 patients underwent intervertebral disk replacement by artificial prostheses in the Department of Spinal Neurosurgery in Burdenko Neurosurgical Institute (Moscow, Russia). Analysis of results of treatment was performed using multidimensional assessment scales.

[Stimulation of tissue lymphatic drainage in the treatment of patients with arterial diseases].

The results of treatment of 17 patients with endarteritis obliteran and 44 patients with atherosclerosis obliteran of the lower limbs were analysed. The complex of therapeutic measures included direct and indirect stimulation of lymphatic drainage in the tissues. The effect of lymphostimulation on regional hemodynamics, microcirculation, and metabolism in the tissues of the ischemic lower limb are appraised.

[The lymphatic system of the lower extremities in patients with obliterating diseases of the terminal portion of the aorta and its branches].

The paper deals with the results of X-ray lymphographic and morphological studies of the peripheral lymphatic system in 82 patients with various stages of chronic lower extremity arterial insufficiency. Destructive and sclerotic changes in lymphatic vessels, inguinal lymph nodes, and impairments in lymph flow whose severity was in proportion to the stage of chronic ischemia were detected. The associated immune, barrier-filtration and transport dysfunctions called for their adequate correction.

[Status of lymphatic vessels, lymph flow and lymph toxicity in patients with obliterating arterial diseases of the lower extremities].

The condition of the lymph vessels, the lymph flow, and the toxicity of peripheral lymph were studied in 46 patients with obliterating diseases of the arteries of the lower limbs. The results of the study showed the severity of the destructive changes in the peripheral lymphatic system to be directly dependent on the severity of the arterial ischemia of the limb. Block of the lymphatic system, deceleration of the lymph flow, and changes in the lymph vessels themselves lead to deterioration of the tissue drainage function and intensification of regional endotoxicosis.

[Evaluation of the results of arterial reconstructions supplemented by the creation of an arteriovenous anastomosis].

Arterial reconstructions supplemented with arteriovenous anastomosis were studied experimentally. The ischemic changes in the operated dog limb were evaluated by various methods, including electronic diagnostic technique. When the diameter of arteriovenous anastomosis was equal to 40-60 per cent of arterial graft diameter, the best postoperative results were observed.

[Endovascular balloon dilatation in the treatment of atherosclerotic lesions of the iliac artery].

Roentgen-endovascular balloon dilatation was used in 16 patients with segmentary stenoses and occlusions of arteries and lower extremity ischemias. The results obtained suggest high efficiency of roentgen-endovascular balloon dilatation for the reestablishment of major blood flow.

[Transcutaneous intravascular balloon dilatation in renal artery stenosis and arterial hypertension].

In 20 patients with stenosis of the renal artery and arterial hypertension Gruentzig balloon catheter was introduced transcutaneously into the artery with subsequent dilatation. In 2 cases arterial pressure became normal, in 8 the course of the disease improved, in 4 high hypertension was retained but responded to hypotensive agents, in 2 there was no effect, and in 4 balloon dilatation could not be carried out due to the impossibility of pushing the catheter through the stenosed segment of vessel. According to the data of renal scintigraphy plasma flow on the affected side rose by 16-66% after dilatation as compared to the initial figures, there was no significant change in the contralateral kidney.