Publications by authors named "Kung Boom Ting"

Article Synopsis
  • Ollier's disease is a rare, nonhereditary condition caused by mutations in IDH1 and IDH2 genes, usually showing symptoms in early life and characterized by multiple enchondromas on one side of the body.
  • Diagnosis involves clinical evaluations and imaging techniques like radiology, and it's crucial to monitor the condition due to the risk of enchondromas turning into malignant chondrosarcomas.
  • The case report focuses on a 25-year-old male with swellings in specific areas, highlighting the importance of bone scans and plain X-rays in managing his multiple enchondromas.
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Article Synopsis
  • Phyllodes tumor is a rare type of breast tumor that can spread to other parts of the body, mostly the lungs, bones, and liver.
  • A 52-year-old woman had this tumor removed from her breast but later found out it had spread to her lungs and many other organs.
  • Doctors used special scans to discover the new places where the tumor had spread within two years after her surgery.
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An 18-year-old male with multiple endocrine neoplasm type 1 (MEN1) syndrome presented with hyperparathyroidism. Parathyroidectomy was performed. Patient complained of bone pain afterwards, multiple imaging modalities revealed features of osteitis fibrosa cystica and biochemical profile showed features of hungry bone syndrome.

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Objectives: The study aimed to evaluate the frequency of incidental suspicious lesions detected by flourine-18 fluorodeoxyglucose PET/computed tomography ( 18 F-FDG PET/CT) scans done for staging or restaging in adult cancer patients. We further determined the detection rate of synchronous and metachronous malignancies in these suspicious lesions after further investigations.

Materials And Methods: This retrospective analysis evaluated the consecutive patients with 18 F-FDG PET/CT scans done in Queen Elizabeth Hospital (QEH), Hong Kong between July 2021 and June 2022.

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Article Synopsis
  • The study conducts a systematic review and meta-analysis to evaluate the effectiveness of 18 F-FDG PET imaging in identifying brain metastases arising from various cancers, revealing potential differences in imaging outcomes based on the type of cancer.
  • Among the 2227 patients analyzed from 11 studies, the findings indicated a low sensitivity (44%) but high specificity (99%) of FDG PET for detecting brain metastases, with significant variability in results across studies.
  • The analysis suggests that awareness of asymmetrical hypometabolism could enhance the sensitivity of FDG PET, indicating a need for further research to refine diagnostic techniques.
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Interpretation of FDG PET images in oncology patients is in general a visual exercise of search for focal increased uptake (hypermetabolism). However, in some cases, hypometabolism (focal decreased uptake) can matter as much as hypermetabolism. We report three cases of FDG PET studies for oncological indications.

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This case report illustrates a rare case of dermatopathic lymphadenitis with interval F-fluorodeoxyglucose positron emission tomography/ computed tomography performed. The clinical presentation, imaging, and histological findings are described. We discuss the diagnostic challenges in this case.

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Objective: Salivagram is one of the imaging modalities to detect pulmonary aspiration in children. This study aims to optimize the classification of pulmonary aspiration detected by salivagram with a semi-quantitative analytical method.

Methods: This is a retrospective study involving 737 patients (471 males, 266 females; aged 1 month to 8 years; mean age 5.

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For decades, conventional nuclear medicine techniques have been utilized for the assessment of many infectious and inflammatory diseases. Most of these techniques have limitations such as the relatively low spatial resolution, being time consuming and low sensitivity or specificity. In recent years, FDG-PET/CT has shown promising role in the management of such diseases.

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Article Synopsis
  • The study focuses on identifying factors that impact progression-free survival in patients with metastatic lung adenocarcinoma treated with tyrosine kinase inhibitors (TKIs).
  • Statistical analysis of 41 patients revealed that primary tumor SUV, serum CEA levels, gender, and smoking history are significant prognostic indicators.
  • Specifically, lower SUV and serum CEA levels, being female, and having a history of never smoking suggest a better response to TKI treatment.
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A 72-year-old gentleman underwent myocardial perfusion scintigraphy (MPS) for sinus tachycardia of unknown cause. Baseline electrocardiography (ECG) showed sinus tachycardia and electrical alternans. Thallium-201 stress-redistribution MPS was performed with dipyridamole stress.

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The aim of this retrospective study is to evaluate the clinical impact and efficacy of fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET/CT) on management decisions for patients suffering from clinically operable non-small-cell lung cancer (NSCLC). A retrospective review of 186 potentially operable NSCLC patients who underwent whole-body PET/CT examination in 2012 was performed. The patients were further analyzed via the electronic patient record (ePR) system for relevant findings.

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This case report explores the potential role of FDG PET/CT in HIV -associated systemic non-Hodgkin's lymphoma (HIV-NHLs). In our locality, there are a cumulative total of 5523 reported HIV infections cases since 1984. We reported a case of HIV-related Burkitt's lymphoma (BL) and a case of diffuse large B-cell lymphoma (DLBCL) that underwent PET/CT examination in our PET centre.

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To determine the prevalence of incidental finding of unknown cerebral metastases and explore the clinical impact of detecting unknown brain metastases among individuals underwent whole body fluorine 18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) with brain included in field of view. A retrospective review of 1876 patients who underwent whole body PET/CT examination in our clinical PET center for oncological evaluation from January 2009 to September 2009 was performed. The total number and prevalence of unknown brain metastases detected by PET/CT were calculated.

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