Long-term effectiveness of omalizumab treatment in Thai severe asthmatic patients: A real-life experience.

Background: To evaluate long-term effectiveness of omalizumab in 'real-life' setting of Thai asthmatic patients.

Methods: We conducted multi-center, observational study in severe asthma patients who received omalizumab in Thailand. Outcomes were asthma exacerbation (hospitalization and ER visit), asthma control test (ACT), and daily ICS dose.

Exertional heatstroke: early recognition and outcome with aggressive combined cooling--a 12-year experience.

Objective: To determine the clinical outcomes of an aggressive combined cooling technique for exertional heatstroke in Thailand.

Methods: We analyzed patients who were diagnosed with exertional heatstroke between 1995 and 2007. Outcomes were assessed both in hospital and at 3 months follow-up.

An outbreak of botulism in Thailand: clinical manifestations and management of severe respiratory failure.

Background: Northern Thailand's biggest botulism outbreak to date occurred on 14 March 2006 and affected 209 people. Of these, 42 developed respiratory failure, and 25 of those who developed respiratory failure were referred to 9 high facility hospitals for treatment of severe respiratory failure and autonomic nervous system involvement. Among these patients, we aimed to assess the relationship between the rate of ventilator dependence and the occurrence of treatment by day 4 versus day 6 after exposure to bamboo shoots (the source of the botulism outbreak), as well as the relationship between ventilator dependence and negative inspiratory pressure.