Publications by authors named "Kun-Xia Hu"
Article Synopsis
- The study focused on creating a dioscin nanosuspension (Dio-NS) that improves its solubility and effectiveness for oral administration, as well as evaluating its effects on liver protection.
- Researchers optimized manufacturing parameters and ingredient concentrations using specific experimental methods to achieve a nanosuspension with favorable particle size and stability.
- Findings showed that Dio-NS had better dissolution compared to other forms, and it effectively protected against liver damage in mice, similar to an established medication, suggesting potential for further research on how it is absorbed in the body.
Exploring Pharmacological Mechanisms of Xiang Ju Tablets in the Treatment of Allergic Rhinitis via a Network Pharmacology Approach.
Evid Based Complement Alternat Med
September 2019
Article Synopsis
- - This study investigates the therapeutic potential of Xiang Ju tablets for treating allergic rhinitis (AR) by pinpointing targets linked to both the disease and the tablets through various databases.
- - An interaction network was created to analyze the core therapeutic targets of Xiang Ju tablets, leading to the identification of the top five targets: CXCL8, IL1B, IL6, IL10, and TNF.
- - The findings highlight biological functions related to cytokine production and signaling pathways involved, determining how Xiang Ju tablets may effectively act against AR through specific cellular processes and activities.
[Preparation and evaluation of dioscin nanostructured lipid carriers].
Zhongguo Zhong Yao Za Zhi
October 2017
In this report, a heat and high-pressure homogenization method was used to prepare dioscin nanostructured lipid carriers, and the formulation of dioscin nanostructured lipid carriers was optimized by central composite design-response surface methodology. In vitro evaluation data showed that the preparation of dioscin nanostructured lipid carriers under optimal process by central composite design-response surface methodology had a spherical shape and homogeneous size distribution, with a particle size of (90.9±0.
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