Publications by authors named "Kun Song Lee"

Article Synopsis
  • - The study analyzed pediatric invasive bacterial infections (IBIs) in children over 25 years (1996-2020) in Korea, highlighting changes in the types of bacteria causing these infections.
  • - A total of 2,195 IBI cases were recorded, with specific bacteria being more common in different age groups: (e.g., Streptococcus pneumoniae in younger children and Staphylococcus aureus in older ones).
  • - Findings indicate a decrease in certain bacteria (like Haemophilus influenzae) and an increase in others (such as Streptococcus pyogenes) before the COVID-19 pandemic, providing important baseline data for understanding IBI trends post-pandemic.
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Objectives: Invasive bacterial infection (IBI) causes a significant burden in infants. In this study, we analyzed changes in epidemiology of IBI among infants in Korea.

Methods: A retrospective multicenter-based surveillance for IBIs in infants <3 months of age was performed during 2006-2020.

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Background: Midkine (MDK), one of the heparin-binding growth factors, is highly expressed in multiple organs during embryogenesis. Plasma concentrations have been reported to be elevated in patients with a variety of malignancies, in adults with obesity, and in children with short stature, diabetes, and obesity. However, the concentrations in healthy children and their relationships to age, nutrition, and linear growth have not been well studied.

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Introduction: This study was performed to determine whether the disturbed maturation of oligodendrocyte (OL) progenitors might be related to lipopolysaccharide (LPS)-induced hypomyelination.

Material And Methods: We created organotypic cultures of forebrain slices from neonatal rats and explored the morphological changes of glial cells expressing tumour necrosis factor  (TNF-) following LPS exposure.

Results: We observed marked activation of glial fibrillary acidic protein-positive astrocytes and OX42-positive microglia co-labelled with TNF- four days following LPS exposure.

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Background: Invasive bacterial infections in apparently immunocompetent children were retrospectively analyzed to figure causative bacterial organisms in Korea.

Methods: A total of 947 cases from 25 university hospitals were identified from 2006 to 2010 as a continuance of a previous 10-year period study from 1996 to 2005.

Results: Escherichia coli (41.

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Article Synopsis
  • - The study investigated changes in pneumococcal serotypes in children with invasive disease in Korea after the introduction of 10- and 13-valent vaccines between 2011 and 2013, involving 75 cases from 25 hospitals.
  • - Serotype 19A was most prevalent (32.0%), while PCV7 serotypes made up only 14.7% of isolates; however, non-vaccine types increased significantly during this period.
  • - While serotype 19A showed a decreasing trend over the study years, the emergence of non-PCV13 types became more prominent, indicating the need for ongoing monitoring of vaccine impacts.
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Peutz-Jeghers syndrome (PJS) is a very rare genetic disorder. PJS carries a high risk of developing gastrointestinal (GI) cancer or non-GI cancer with advancing years. However, major symptoms of PJS in childhood are obstruction, intussusception, and bleeding from hamartomatous intestinal polyps which in majority of cases are not related to cancer.

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Purpose: The use of dietary supplements (DS) has increased in most nations. We investigated the amount of DS intake in the Korean population by analyzing a national survey, to support the preparation of a national institutional strategy regarding DS intake and marketing.

Methods: The data of the fifth Korea National Health and Nutrition Examination Survey (a year between 2010 and 2012) were investigated, analyzing the rate of DS intake, and the characteristics of the intake group and non-intake group in Korean preschool children.

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Purpose: The oil spill from the Heibei Spirit in December 2007 contaminated the Yellow Coast of South Korea. We evaluated the respiratory effects of that spill on children who lived along the Yellow Coast.

Methods: Of 662 children living in the area exposed to the oil spill, 436 (65.

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Chronic diarrhea is defined as passing watery stools that lasts for more than 2 weeks. Persistent diarrhea belongs to chronic diarrhea and is a chronic episode of diarrhea of infectious etiology. The etiology of chronic diarrhea is varied.

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Background/aims: Acute hepatitis A (HAV) is markedly increasing recently on. Some patients with acute hepatitis A show severe clinical course. The seroprevalence rate of IgG anti-HAV has been changing with the regions and the times.

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Objective: The purpose of this study was to evaluate the chest radiographic and CT findings of novel influenza A (H1N1) virus infection in children, the population that is more vulnerable to respiratory infection than adults.

Materials And Methods: The study population comprised 410 children who were diagnosed with an H1N1 infection from August 24, 2009 to November 11, 2009 and underwent chest radiography at Dankook University Hospital in Korea. Six of these patients also underwent chest CT.

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A congenital intrahepatic portosystemic shunt is a rare anomaly; but, the number of diagnosed cases has increased with advanced imaging tools. Symptomatic portosystemic shunts, especially those that include hyperammonemia, should be treated; and various endovascular treatment methods other than surgery have been reported. Hepatic masses with either an intra- or extrahepatic shunt also have been reported, and the mass is another reason for treatment.

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Tracheal diverticulum is a rarely encountered entity characterized by single or multiple invaginations of the tracheal wall. Two types of tracheal diverticula exist: congenital and acquired. We report a case of a pulmonary artery sling with an aberrant right subclavian artery associated with tracheal diverticulum.

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