Comparison of ultrasound biomicroscopic changes after glaucoma triple procedure and trabeculectomy in eyes with primary angle closure glaucoma.

Purpose: To evaluate ultrasound biomicroscopy changes in the anterior chamber angle (ACA) configuration after glaucoma triple procedure (GTP), compared with those seen after trabeculectomy, in eyes with primary angle closure glaucoma (PACG).

Methods: Twenty-nine PACG eyes that underwent GTP were compared with 27 eyes that underwent trabeculectomy only, using ultrasound biomicroscopy. Anterior segment parameters such as anterior chamber depth, angle opening distance (AOD500), trabecular ciliary process distance, trabecular iris angle, iris ciliary process distance, iris thickness along the trabecular ciliary process distance line (ID1), scleral ciliary process angle, scleral iris angle, and angle recess area were measured preoperatively and at 3 months postoperatively; these parameters were then compared between the procedures.

Ultrasound biomicroscopic changes after laser iridotomy or trabeculectomy in angle-closure glaucoma.

This study was performed to demonstrate the ultrasound, biomicroscopic and dimensional changes of angle structure after laser iridotomy (LI) and primary trabeculectomy (PT) in primary angle-closure glaucoma (PACG). Angle-opening distance at a point 500 m from the scleral spur (AOD500), trabecular-iris angle (theta1), trabecular ciliary process distance (TCPD), ciliary process-iris angle (CPI), iris thickness (ID1, ID3), length of iris-lens contact distance (ILCD) and anterior chamber depth (ACD) were assessed before and after each procedure. Thirteen patients with LI and 16 with PT were prospectively enrolled.

Effect of human RAD50 gene therapy on glaucoma filtering surgery in rabbit eye.

Purpose: To investigate the antiproliferative effects of the subconjunctival injection of human RAD50 (hRAD50) on fibroblasts after glaucoma filtering surgery.

Methods: After glaucoma filtering surgery in normal rabbit eye, the subconjunctival injection of hRAD50 was performed. Morphologic changes in the subconjunctival area of hRAD50-treated eyes were compared with those of mitomycin C (MMC)-treated and control eyes using light and electron microscopy.

Ultrasound biomicroscopic dimensions of the anterior chamber in angle-closure glaucoma patients.

In order to evaluate the morphologic types of appositional angle-closure glaucoma, biometric measurements were made in angle-closure glaucoma patients using Ultrasound biomicroscopy (UBM). Twenty-six patients with primary angle-closure glaucoma and 21 cataract patients with as a control group were examined. The angle-closure glaucomatous eyes were classified as type B in which the angle closure started at the bottom of the angle and type S in which the angle closure occurred in the vicinity of Schwalbe's line.

Postnatal expression and distribution of Refsum disease gene associated protein in the rat retina and visual cortex: effect of binocular visual deprivation.

Previously, phytanoyl-CoA alpha-hydroxylase-associated protein 1 (PAHX-AP1) was isolated as a novel neuron-specific protein to interact with Refsum disease (RfD) gene PAHX. Its expression in the brain increased after eyelid opening, and the elevated level was maintained through adulthood. In this report, to verify the hypothesis that light could trigger this increase, we have examined the developmental distribution pattern of PAHX-AP1 in rat retina and visual cortex, and changes of its expression by binocular deprivation.