Publications by authors named "Kumudini Panigrahi"
Article Synopsis
- - Dermatophytosis is a widespread fungal infection affecting about 20-25% of the global population, with significant prevalence in Odisha, India, where there is limited data on its clinic-mycological patterns.
- - A two-year cross-sectional study was conducted with participants aged 18-65 who had active dermatophyte infections, involving clinical examinations and mycological assessments.
- - The results revealed that the most common fungal isolate was identified at 21.7%, indicating that different dermatophyte species have varying prevalence rates, with specific trends noted in this region of eastern India.
Methicillin-resistant (MRSA) is one of the major causes of hospital and community-acquired infections. Fewer drugs, such as vancomycin, teicoplanin, and daptomycin, are effective against it, but they come with high toxicity. Fifth-generation cephalosporins like ceftaroline and second-generation cefuroxime are effective against MRSA.
View Article and Find Full Text PDFIntroduction: The number of neonatal cerebrospinal fluid (CSF) samples sent from the neonatal intensive care unit (NICU) for cytologic examination is rising, warranting accurate analysis and interpretation of the same. This study was taken up to assess the usefulness of CSF cell count and cytology in NICU settings, as it can be used even in a resource-limited setting.
Aim And Objective: 1) To study the prevalence of cell count and cytologic changes in CSF from NICU and assess their usefulness in correlation to C-reactive protein, CSF neutrophil percentage, blood, CSF culture, and other biochemical parameters.
Article Synopsis
- Colistin is the last treatment option for infections from multi-drug resistant gram-negative bacteria, but recently there has been a rise in resistance to this drug, particularly in clinical settings.
- A study carried out in an ICU in Eastern Odisha, India, from March 2019 to February 2020, found that 19.6% of the MDR gram-negative isolates were resistant to colistin, with high occurrences in respiratory infections and neurology patients.
- The majority of patients (74.2%) recovered, and interestingly, a significant number of ICU patients (57.9%) had no co-morbidities, indicating that colistin resistance is an emerging concern in managing infections in the ICU.
Article Synopsis
- The study compares the performance of the Abbott ID NOW test, a rapid point-of-care method, with the standard RT-PCR test for detecting SARS-CoV-2, the virus causing COVID-19, supported by WHO recommendations.
- A cross-sectional study involving 259 patients was conducted, and nasopharyngeal swabs were analyzed using both tests after obtaining proper ethical approval.
- Results showed that the ID NOW test had a sensitivity of 87% and specificity of 98%, making it a reliable rapid testing option compared to the standard RT-PCR method.
We investigated the persistence of the vaccine-induced immunoglobulin G (IgG) antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among healthcare workers (HCWs) in Odisha who received a complete dose of either Covaxin or Covishield vaccine. This 24-week longitudinal cohort study was conducted from January to July 2021 with participants from 6 healthcare and research facilities of Odisha to understand the dynamicity of the vaccine-induced IgG antibodies against SARS-CoV-2 after the complete dose of vaccines. Serum samples were collected from 614 participants during each follow-up and were tested in two chemiluminescent microparticle immunoassay (CLIA)-based platforms to detect SARS-CoV-2 antibodies both qualitatively and quantitatively.
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