Publications by authors named "Kumiko Omine"
Rationale: Although the mortality of severe coronavirus disease 2019 (COVID-19) has decreased after the emergence of the Omicron variant, it remains high in patients on hemodialysis (HD). Remdesivir (RDV) is considered as the first line drug for hospitalized COVID-19 patients, however the evidence regarding the usage in HD patients is lacking because clinical trials of RDV have excluded HD patients for safety reasons. Thus, accumulation of knowledge on the regimen, efficacy, and tolerability of RDV in HD patients is important.
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- Autoimmune factor V deficiency (AiFVD) is a rare bleeding disorder caused by inhibitors that target factor V, affecting blood clotting ability.
- In this case, an 89-year-old man experienced excessive bleeding during a surgical procedure for hemodialysis, which was linked to prolonged clotting times and the presence of factor V inhibitors and autoantibodies.
- Treatment with oral prednisolone led to improvement in his bleeding symptoms and normalization of his coagulation tests after 34 days, highlighting the importance of diagnosing AiFVD in similar patients undergoing hemodialysis.
Herein, we describe a rare case of Corynebacterium jeikeium endocarditis that silently progressed in a 65-year-old man undergoing hemodialysis. Because routine monthly blood examination revealed high C-reactive protein levels, blood cultures were collected, although he had no symptom and was afebrile. After 2 days, a Gram-positive rod was detected in one set of the blood culture.
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