Publications by authors named "Kumiko Negishi"
Article Synopsis
- Streptococcus suis is a gram-positive bacterium that can cause serious infections like bacterial meningitis and sepsis in humans, often transmitted through raw pork or exposure to pigs.
- A case study highlights a 38-year-old woman who developed septic shock after consuming raw pork, and although medical interventions were aggressive, her condition worsened rapidly.
- The report emphasizes the importance of timely recognition of such zoonotic pathogens and suggests that peripheral blood smears can help diagnose infections even before blood culture results are available.
Gemella is a facultative anaerobic Gram-positive coccus and a rare cause of infective endocarditis (IE). Gram staining may eventually misidentify the organism, which tends to easily decolorize and manifest as either Gram-negative or Gram-variable. Commercial biochemical tests are often used to identify Gemella, but the methods they employ sometimes lack accuracy.
View Article and Find Full Text PDFBackground: The prevalence of invasive fungal infection is increasing. An effective diagnostic test is required to identify and treat them successfully.
Methods: All autopsy records at our hospital for the period from January 2000 through December 2005 [corrected] were reviewed for cases of invasive fungal infection.
Article Synopsis
- A rare case of recurrent pulmonary nocardiosis (PN) is reported in a patient who received a hematopoietic stem cell transplant and was being treated for bronchiolitis obliterans linked to chronic graft-versus-host disease (cGVHD).
- The patient initially responded well to meropenem therapy, but PN recurred three times despite attempts to manage it with different oral antibiotics based on susceptibility testing.
- Frequent recurrences were likely due to low antibiotic blood levels and poor gastrointestinal absorption related to the ongoing effects of cGVHD.
We report the successful treatment of a disseminated Fusarium infection with skin manifestations in a severely neutropenic patient. A 51-year-old man with acute myeloblastic leukemia (M4) underwent two courses of remission induction therapy with cytarabine and daunorubicin. Despite prophylactic treatment with tosufloxacin and micafungin, the patient developed a febrile scrotal ulcer.
View Article and Find Full Text PDFTo assess the merit of serum HIV-1 RNA quantification in detecting acute HIV infection, we reviewed the results of HIV-1 RNA assay and antibody tests in all patients who received those tests at our hospital from August 1999 to December 2004. Of 3530 such patients, five were sero-negative and PCR-positive with more than 105 copies/ml at initial examination. Four of them had HAART and followed a favorable course; they were later confirmed to be sero-positive by Western blotting.
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