Vascular dysfunction in women with recurrent pregnancy loss: Possible association with antiphospholipid antibodies.

Objective: Antiphospholipid antibodies (aPL) are recognized to have a pivotal role in recurrent pregnancy loss (RPL) and cardiovascular disease. Therefore, we assessed the vascular function of women with RPL and examined the association with each type of aPL.

Methods: In this retrospective study, 569 women with RPL and 55 healthy women who had never experienced pregnancy loss were recruited.

Altered autonomic nervous system activity in women with unexplained recurrent pregnancy loss.

Aim: Autonomic nervous system activity was studied to evaluate the physical and mental state of women with unexplained recurrent pregnancy loss (RPL).

Methods: Heart rate variability (HRV) is a measure of beat-to-beat temporal changes in heart rate and provides indirect insight into autonomic nervous system tone and can be used to assess sympathetic and parasympathetic tone. We studied autonomic nervous system activity by measuring HRV in 100 women with unexplained RPL and 61 healthy female volunteers as controls.