Publications by authors named "Kumi Yamada"

The effects of walking on mental health problems among healthy Japanese workers are not fully understood. In the present study, we investigated the effects of a four-week walking program on the psychological functioning of a nonclinical sample of healthy workers in Japan.A total of 606 healthy subjects were enrolled in the study and were evaluated by the Zung Self-rating Depression Scale (SDS) and the Social Adaptation Self-evaluation Scale (SASS) both before and after the walking program.

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To clarify the involvement of 5-hydroxytryptamine (5-HT) in promotion of thrombogenesis in diabetes, we examined the inhibitory effect of sarpogrelate, a 5-HT(2A) receptor antagonist, on thrombus formation in diabetic rats. In streptozotocin-induced diabetic rats, polyethylene tube-induced thrombus formation was enhanced compared with that in normal rats. The thrombogenesis was inhibited by sarpogrelate; cilostazol, a PDE3 inhibitor; and aspirin, a COX inhibitor, by 75.

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