Publications by authors named "Kumbaracı B"
Article Synopsis
- - This study investigated the link between exposure to persistent organic pollutants (POPs) and the development of kidney tumors, analyzing samples from patients who had kidney surgery and a control group for comparison.
- - Researchers measured POP concentrations in blood and various kidney-associated tissues, and assessed urinary markers indicating oxidative stress and potential DNA damage.
- - Findings suggested a connection between high levels of certain POPs and an increased risk of kidney cancer, with specific genetic factors, like the GSTT1 null polymorphism, potentially influencing this risk.
Article Synopsis
- The study aims to compare the effectiveness of epoprostenol and Helixor in treating avascular necrosis of the femoral head in rabbits, with the hypothesis that Helixor may be as effective as epoprostenol.
- A group of 45 rabbits was divided into three groups: a control group, one treated with Ilomedin (an epoprostenol analogue), and another with Helixor. Various factors such as bone necrosis, repair, and cartilage damage were examined microscopically.
- Results showed that while the control group had more necrosis, the treatment groups had improved bone marrow cellularity and less cartilage damage, with Helixor showing the most significant
Cutaneous amyloidosis (CA) is defined by the accumulation of amyloid in the dermis; it might be primary or secondary. The diagnosis is based on histopathological findings with the demonstration of amyloid deposits, confirmed by Congo red stain under the polarized light. Studies on other diagnostic markers are ongoing in the literature.
View Article and Find Full Text PDFObjectives: Parathyroid carcinoma (PC) is a rare parathyroid tumor compared to parathyroid adenoma (PA) and atypical parathyroid adenoma (APA). Recent studies have suggested parafibromin has a role in the differential diagnosis of parathyroid tumors. We sought to determine the role of parafibromin as well as galectin-3, Ki-67, and HBME-1 as diagnostic markers in the differential diagnosis of parathyroid tumors.
View Article and Find Full Text PDFBackground: Parafibromin is a recently defined tumor suppressor gene. The aim of our study was to determine the relationships of parafibromin expression in urothelial carcinomas (UCs) with prognostic parameters and to evaluate the use of parafibromin as a potential marker of UC.
Methods: Parafibromin expression was assessed in 49 UC specimens using immunohistochemistry.
Small cell carcinoma (SmCC) is a rare and aggressive neuroendocrine carcinoma of the bladder. Neuroendocrine carcinomas expressing somatostatin receptors (SSTR) in other viscera such as lung, pancreas, and gastrointestinal system respond to therapy with somatostatin analogs. In the present study, expressions of SSTRs 1 to 5 including type 2A are investigated by immunohistochemistry (IHC) and their relationship with clinicopathologic factors was evaluated.
View Article and Find Full Text PDFObjective: Cellular blue nevus differs from the classic blue nevus with characteristics such as large size, cellularity, intense pigmentation, and growing pattern with subcutaneous infiltration. It is a dermal melanocytic tumor that can be confused with melanoma due to the atypia it may contain.
Material And Method: Hematoxylin-eosin and MIB-1 stained slides of 21 cases diagnosed between 2000-2014 were re-evaluated.
An 11-year-old girl with vesicles and eroded lesions on her oral mucosa and tongue was diagnosed as having pemphigus vulgaris. The diagnosis was confirmed by histopathologic and immunofluorescence studies. The patient was successfully treated with methylprednisolone and azathioprine.
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