Publications by authors named "Kumari L Andarawewa"
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Synopsis of recent research by authors named "Kumari L Andarawewa"
- Kumari L Andarawewa's research primarily focuses on the role of transforming growth factor beta (TGF-β) in cancer biology, particularly its influence on epithelial-to-mesenchymal transition (EMT) and tumor progression, as demonstrated in various studies involving mammary epithelial cells and melanoma.
- Her investigations reveal that ionizing radiation can sensitize nonmalignant cells to undergo TGF-β-mediated EMT, potentially impacting tumorigenesis and responses to therapy, highlighting both the tumor suppressor and promoter functions of TGF-β during cancer development.
- Additionally, Andarawewa explores therapeutic strategies, such as the use of integrin agonists and matrix metalloproteinase inhibitors in enhancing chemotherapy efficacy for metastatic cancers, indicating a multifaceted approach to improving cancer treatment outcomes.
