Acute embolic infarcts of bilateral cerebellar lobes, cerebral peduncles, thalami and left parietal lobe cortex following HIPEC surgery.

Cytoreductive surgery and intraoperative, intraperitoneal hyperthermic chemoperfusion (hyperthermic intraperitoneal intraoperative chemotherapy) are commonly used for the management of peritoneal surface metastases. We describe a case of acute embolic infarcts in bilateral cerebellar lobes, cerebral peduncles, thalamus and left parietal lobe cortex in a postmenopausal woman in her 50s diagnosed with bilateral ovarian mucinous adenocarcinoma with peritoneal metastasis under general anaesthesia.

Unraveling the intricate tapestry of bamboo transcription factors in abiotic stress signaling and resilience with special reference to moso bamboo family.

The abiotic stress tolerance mechanism in plants is regulated by multiple physiological, biochemical, and molecular processes; hence, omics approaches to underpin these mechanisms are essential. It is clear that transcription factors (TFs) are one of the fundamental molecular switches that play a crucial role in modulating, regulating, and orchestrating plants in response to various climatic vagaries. Several reports are available now, focusing on understanding the roles of TFs, including those in Poaceae family in regulating different biological processes and stress responses.

A study of autoimmune thyroid disease in pregnant women and its effect on fetal and maternal outcome.

Introduction: Anti-thyroid antibodies not only cause thyroid dysfunction but have independent adverse outcomes in the fetus and mother during pregnancy and after birth. Chronic lymphocytic thyroiditis as a presentation of immune system deregulation may be associated with a generalized activation of the immune system at the fetus-maternal unit, the placenta. This interference could be associated with pregnancy morbidities in m o t h e r a n d fetus.

Anthocyanin-rich black wheat as a functional food for managing type 2 diabetes mellitus: a study on high fat diet-streptozotocin-induced diabetic rats.

: Type 2 Diabetes Mellitus (T2DM) is associated with insulin resistance, hyperglycemia, and hyperlipidemia. Anthocyanins, which are natural antioxidants, have been reported to manage T2DM-related complications. However, the potential of anthocyanin-rich black wheat as a functional food for managing diabetes remains unexplored.

Multichromophoric Triad and g-CN Composite as Efficient Heterogeneous Photocatalyst for Oxidative Amidation of Aldehydes.

In this work, we have synthesized a multichromophoric light-harvesting antenna, namely, triad, consisting of naphthalene monoimide (NMI) and perylene monoimide (PMI) chromophores. Triad was adsorbed onto polymeric graphitic carbon nitride (g-CN) to form triad/g-CN composite, utilized as a photocatalyst for oxidative amidation reaction. This composite photocatalyst demonstrated enhanced photocatalytic activity for the conversion of a variety of aldehydes to amides, leading up to 82 % product yield compared to only g-CN or only triad as photocatalysts.

Role of chemokines in aging and age-related diseases.

Chemokines (chemotactic cytokines) play essential roles in developmental process, immune cell trafficking, inflammation, immunity, angiogenesis, cellular homeostasis, aging, neurodegeneration, and tumorigenesis. Chemokines also modulate response to immunotherapy, and consequently influence the therapeutic outcome. The mechanisms underlying these processes are accomplished by interaction of chemokines with their cognate cell surface G protein-coupled receptors (GPCRs) and subsequent cellular signaling pathways.

Naphthalene Monoanhydride and Perylene Composites for Efficient Photocatalytic Hydrogen Evolution and Metal-Free Heterogeneous Oxidative Amidation.

This study explores the synthesis of two visible light active organic chromophore-based composites using naphthalene monoanhydride () and 1,7-dibromoperylene monoanhydride diester (). These chromophores feature favorable optical and electronic properties and polyaromatic skeletons with anhydride functionalities that facilitate π-π interactions between the chromophore and polymeric carbon nitride () or covalent connections of chromophores with NH groups of . Accordingly, heterogeneous chromophore- composite photocatalysts namely, and were prepared by adopting calcination (c) and composites and were prepared by physical adsorption (a) methods.

Synthesis of fluorometric carbon nano dots(CNDs) for selective sensing of biologically important Fe and Cu metal ions and evaluating their antioxidant capacity.

In this research, CNDs were prepared by a green and cost effective method using Cinnamomum Tamala (bay leaf) as carbon sources. TEM, UV, FTIR, ZETA Potential, PL and Fluorescence methods were used to characterize the produced CNDs and the average particle size is 3.42 nm.

T cell factor 1 (TCF-1) defines T cell differentiation in colorectal cancer.

The presence of precursor to exhausted (T) CD8 T cells is important to maintain robust immunity following treatment with immune checkpoint inhibition (ICI). Impressive responses to ICI are emerging in patients with stage II-III mismatch repair (MMR)-deficient (dMMR) colorectal cancer (CRC). We found 64% of dMMR and 15% of mismatch repair-proficient (pMMR) stage III CRCs had a high frequency of tumor infiltrating lymphocytes (TIL-hi).

Chemical characterization and biological activity of Curvularia Lunata, an endophytic fungus isolated from lemongrass (Cymbopogon citratus).

Exploration of medicinal plants for bioactive-producing endophytic fungi is a relatively unmapped source of pharmaceutically important compounds. In this study, the endophytic fungus Curvularia lunata AREF029 isolated from the medicinal plant Cymbopogon citratus (known as lemongrass) was assessed for its biological activity. The methanolic extract of AREF029 had minimum inhibition concentration (MIC) ranging from 38 to 174 µg/ml against phytopathogenic fungi Alteranria solani, Fusarium oxysporum and Rhizoctonia solani.

New Strategy for Browning Prevention in Apple Pomace Processing and Toxicity Tested in a Rodent Model.

Apple pomace (AP) is a byproduct of apple juice industries, which constitutes around 30% of the original fruit and rich in essential compounds like carbohydrates, phenolics, minerals, and dietary fibers. This study is focused on optimizing the combinational utilization of antibrowning agents like l-cysteine and l-ascorbic acid for the sustainable debrowning of AP with response surface methodology and assessment of its acute toxicity in female rats. In addition, the phytochemical content and antioxidant activity of treated AP were investigated and compared with the untreated control AP.

Exploring the genetic architecture of powdery mildew resistance in wheat through QTL meta-analysis.

Powdery mildew (PM), caused by sp. , poses a significant threat to wheat production, necessitating the development of genetically resistant varieties for long-term control. Therefore, exploring genetic architecture of PM in wheat to uncover important genomic regions is an important area of wheat research.

The long noncoding RNA (LINC-RBE) expression in testicular cells is associated with aging of the rat.

Long noncoding RNAs (lncRNAs) are important regulatory biomolecules responsible for many cellular processes. The aging of mammals is manifested by a slow and gradual decline of physiological functions after adulthood, progressively resulting in age-related diseases. Testis comprises different cell-types with defined functions for producing haploid gametes and androgens in males, contributing gene-pool to the next generation with genetic variations to species for evolutionary advantage.

Substantially altered bacterial diversity associated with developmental stages of litchi stink bug, (Thunberg) (Hemiptera: Tessaratomidae).

The mutualistic symbiotic relationship between insects and bacteria greatly influences the growth and development of host insects. (Thunberg) (Hemiptera: Tessaratomidae), also referred to as the litchi stink bug, has recently been established as an important insect pest of Sonn. and causes substantial yield loss in India.

Morphological and molecular characterization of two species of genus Ageratum.

Background: The species of genus Ageratum (family Asteraceae) are distributed in various parts of the world. Ageratum conyzoides and A. houstonianum are the most commonly occurring species in India.

Unlocking genetic insights: Evaluating wheat RILs for physiobiochemical traits under terminal heat stress conditions.

Background: The increasing impacts of heat stress on wheat production due to climate change has entailed the development of heat-resilient crop varieties. To address this, two hundred recombinant inbred lines (RILs) derived from a cross between WH711/WH1021 were evaluated in a randomized block design (RBD) with two replications at CCSHAU, Hisar, during 2018-19 under heat stress and non-stress conditions. Heat stress was induced by altering the date of sowing so that the grain filling stage coincide with heat stress.

Relationship of emotional intelligence and capability of answering higher-order knowledge questions in physiology among first-year medical students.

Emotional intelligence (EI) has a positive correlation with the academic performance of medical students. However, why there is a positive correlation needs further exploration. We hypothesized that the capability of answering higher-order knowledge questions (HOQs) is higher in students with higher EI.

Molecular rotors of naphthalimide and benzodithiophene as effective solvent polarity probes, temperature sensors, and for g-CN sensitization.

Acceptor-donor-acceptor (A-D-A) molecular rotors have drawn substantial attention for their applications in monitoring temperature variations within cellular microenvironments, biomimetic photocatalysis, and bioimaging. In this study, we have synthesized two novel rotor molecules, NBN1 and NBN2, by incorporating benzodithiophene (BDT) as the donor core and naphthalic anhydride/naphthalimide (NA/NI) moieties as acceptors using Pd-catalyzed Stille coupling reactions. These molecules exhibited distinct charge transfer (CT) behavior in both their absorption and emission spectra and displayed prominent emission solvatochromism.

Meta-QTL and ortho analysis unravels the genetic architecture and key candidate genes for cold tolerance at seedling stage in rice.

Unlabelled: Rice, a critical cereal crop, grapples with productivity challenges due to its inherent sensitivity to low temperatures, primarily during the seedling and booting stages. Recognizing the polygenic complexity of cold stress signaling in rice, a meta-analysis was undertaken, focusing on 20 physiological traits integral to cold tolerance. This initiative allowed the consolidation of genetic data from 242 QTLs into 58 meta-QTLs, thereby significantly constricting the genetic and physical intervals, with 84% of meta-QTLs (MQTLs) being reduced to less than 2 Mb.

Cell-type specific and differential expression of LINC-RSAS long noncoding RNA declines in the testes during ageing of the rat.

Long noncoding RNAs (lncRNAs) have emerged as major regulators of gene expression, chromatin structure, epigenetic changes, post-transcriptional processing of RNAs, translation of mRNAs into proteins as well as contributing to the process of ageing. Ageing is a universal, slow, progressive change in almost all physiological processes of organisms after attaining reproductive maturity and often associated with age-related diseases. Mammalian testes contain various cell-types, vast reservoir of transcriptome complexity, produce haploid male gametes for reproduction and testosterone for development and maintenance of male sexual characters as well as contribute genetic variation to the species.

On estimation of P(Y < X) for inverse Pareto distribution based on progressively first failure censored data.

The stress-strength reliability (SSR) model ϕ = P(Y < X) is used in numerous disciplines like reliability engineering, quality control, medical studies, and many more to assess the strength and stresses of the systems. Here, we assume X and Y both are independent random variables of progressively first failure censored (PFFC) data following inverse Pareto distribution (IPD) as stress and strength, respectively. This article deals with the estimation of SSR from both classical and Bayesian paradigms.