NELL1-Positive HIV-Associated Lupus-Like Membranous Nephropathy with Spontaneous Remission.

Introduction: Kidney biopsy findings in patients with human immunodeficiency virus (HIV) are diverse, and optimal therapy for the various immune complex diseases in the setting of HIV is unknown.

Case Presentation: A man with well-controlled HIV developed nephrotic range proteinuria, and kidney biopsy revealed lupus-like glomerulonephritis with a predominantly membranous pattern of injury. He opted for conservative therapy and experienced spontaneous and sustained remission.

Low oxygen levels caused by Noctiluca scintillans bloom kills corals in Gulf of Mannar, India.

Coral reefs around the world are undergoing severe decline in the past few decades. Mass coral mortalities have predominantly been reported to be caused by coral bleaching or disease outbreaks. Temporary hypoxic conditions caused by algal blooms can trigger mass coral mortalities though are reported rarely.

Marine debris - An emerging threat to the reef areas of Gulf of Mannar, India.

Underwater survey was conducted to assess the accumulation and impact of marine debris in the reef areas of Gulf of Mannar in southeast India. A combination of roving diver technique and belt transect method was applied for the assessment, which was conducted during the period between February 2018 and March 2019. An estimated total reef area of 1152 m has been affected by marine debris.

Seagrass restoration in Gulf of Mannar, Tamil Nadu, Southeast India: a viable management tool.

Seagrass beds are important marine ecosystems that provide significant ecological services. The global decline of seagrass beds is becoming severe due to the increasing pressure of human-induced factors and changing climatic conditions. Restoration of seagrasses is an evolving science that started in 1939.

Anti-LRP2 Nephropathy With Abundant IgG4-Positive Plasma Cells: A Case Report.

In older adults, the most common kidney biopsy diagnoses include pauci-immune crescentic glomerulonephritis, membranous nephropathy, and focal segmental glomerulosclerosis. Recently, investigators described a small series of older patients (aged 66-80 years) with acute kidney injury and a kidney biopsy demonstrating tubular basement membrane (TBM) immune deposits of polytypic immunoglobulin G (IgG) and C3, acute tubular injury, and tubulointerstitial inflammation. They identified a circulating antibody against kidney tubular low-density lipoprotein (LDL) receptor-related protein 2 (LRP2; also known as megalin) in patients' sera and colocalization of LRP2 with IgG in TBM deposits.

Graph Theoretical Analysis, In Silico Modeling, Synthesis, Anti-Microbial and Anti-TB Evaluation of Novel Quinoxaline Derivatives.

Background: We designed to synthesize a number of 2-(2-(substituted benzylidene) hydrazinyl)-N-(4-((3-(phenyl imino)-3,4-dihydro quinoxalin-2(1 H)-ylidene)amino) phenyl) acetamide S1-S13: with the hope to obtain more active and less toxic anti-microbial and anti-TB agents.

Methods: A series of novel quinoxaline Schiff bases S1-S13: were synthesized from o-phenylenediamine and oxalic acid by a multistep synthesis. In present work, we are introducing graph theoretical analysis to identify drug target.

Clinical performance of Class I nanohybrid composite restorations with resin-modified glass-ionomer liner and flowable composite liner: A randomized clinical trial.

Background: Liners play a vital role in minimizing polymerization shrinkage stress by elastic bonding concept and increase the longevity and favorable outcome for composite restorations.

Aims: The aim of this study was to evaluate the clinical performance of nanohybrid composite restorations using resin-modified glass-ionomer and flowable composite liners.

Settings And Design: A single-centered, double-blinded randomized clinical trial, with split-mouth design and equal allocation ratio that was conducted in the Department of Conservative Dentistry and Endodontics.

Late acceleration of glomerular filtration rate decline is a risk for hemodialysis catheter use in patients with established nephrology chronic kidney disease care.

Chronic kidney disease (CKD) patients with established nephrology care have a high rate of tunneled dialysis catheters (TDC) as first vascular access when transitioning to hemodialysis (HD). We sought to identify factors associated with this problem. Patients who started HD and had prior CKD care within our renal clinic were categorized according to access type at incident HD.

Polyethylene glycolated PAMAM dendrimers-Efavirenz conjugates.

Aim: The preparation of novel PEGylated PAMAM (poly-amidoamine) dendrimers for delivery of anti-HIV drug Efavirenz is reported.

Method And Materials: About 5.0 G PAMAM dendrimers are prepared by ethylene diamine core via Michael addition by divergent method.

Maxillofacial trauma in Tamil Nadu children and adolescents: A retrospective study.

Aim: The aim of this retrospective study is to describe the incidence, aetiology, complexity and surgical indications of maxillofacial injuries in children and adolescents population of Tamil Nadu state of india during period of 4 years.

Materials And Methods: A retrospective review was conducted among 500 children and adolescents patients of age group 6 years to 16 years suffered or suffering with maxillofacial and skull fractures presenting to ten Level I trauma centers over a 4 year period.The data collected for this study included age, gender, etiology, associated maxillofacial trauma, anatomic site of fracture and treatment.

Temporal artery vasculitis in young: a report of two cases.

Temporal (giant cell) arteritis is a chronic vasculitis of large and medium sized vessels which usually occurs in individuals above 50 years of age. In patients less than 50 years temporal artery vasculitis is extremely rare. The clinical presentations of the vasculitis in younger patients appear to be different from the older patients.