Publications by authors named "Kumagai Shima"

This report describes six successful pregnancies (five healthy children from four deliveries and two miscarriages) with SrC1(2) oocyte activation using spermatozoa from nine patients with repeated fertilization failure. Oocytes were artificially activated by SrC1(2) 30 min after intracytoplasmic sperm injection (ICSI). Oocytes were placed in 10 mmol/l of SrC1(2) medium for 1 h, rinsed several times, and then cultured in Universal IVF medium.

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Purpose: The aim of this study was to investigate the feasibility of using frozen-thawed testicular sperm as well as the timing of testicular sperm extraction (TESE) in patients with non-mosaic Klinefelter syndrome.

Methods: Intracytoplasmic sperm injection (ICSI) was performed in six of 17 (35%) patients whose sperm was recovered by TESE. Multiple biopsies of both testes were performed on the day of oocyte retrieval in all but one of the six patients.

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Article Synopsis
  • The study aimed to evaluate the effectiveness of low-dose hCG in a GnRH antagonist treatment protocol for women under 40 years old with limited previous IVF cycles.
  • A total of 192 women were divided into three groups: one using a GnRH agonist long protocol, another using GnRH antagonist without low-dose hCG, and the third using GnRH antagonist with low-dose hCG.
  • Results indicated that the low-dose hCG group had better outcomes in terms of oocyte maturation and embryo quality, while also reducing the risk of ovarian hyperstimulation syndrome, although pregnancy rates were similar across all groups.
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Objective: To describe the first case of delivery after the transfer of a single blastocyst derived from a vitrified mature human oocyte.

Design: Case report.

Setting: Private assisted reproduction clinic.

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