Publications by authors named "Kulvara Kittisares"

Introduction: DEL is known to be one of the weakest D variants, which can be detected by the adsorption-elution technique or by molecular study. Currently, in Thailand, we do not routinely test for DEL variants serologically or genetically among serologic RhD-negative blood donors.

Case Presentation: We reported 2 cases of alloimmunization after transfused with Rh DEL, allele, in the Thai population.

View Article and Find Full Text PDF

Current treatment of severe dry eye disease (DED) includes blood-derived eye drops, such as autologous serum (AS), which lubricate the eyes and provide factors that improve ocular surface and aid in wound healing. Recent studies indicated that platelet-rich plasma (PRP) was also effective. This study aims to compare the concentration and stability of epitheliotrophic factors in AS and PRP and their efficacy in DED patients.

View Article and Find Full Text PDF

Objective: Local intramuscular transplantation of granulocyte colony-stimulating factor (G-CSF)-mobilised peripheral blood mononuclear cells (PB-MNC) has been shown to be effective for treating patients with no-option critical limb ischaemia (CLI) who are not considered suitable to undergo surgical bypass or percutaneous transluminal angioplasty. The aim of this study was to investigate the effectiveness and safety of PB-MNCs as a treatment for no-option CLI patients.

Method: This prospective cohort study was conducted between April 2013 and December 2017.

View Article and Find Full Text PDF

Background: Our previous retrospective study demonstrated that NMOSD patients with an acute attack who did not respond to IVMP alone, however, showed further significant improvement after treatment with PLEX at 6 month-follow-up.

Objective: To compare the efficacy between treatments with intravenous methylprednisolone (IVMP) with subsequent add-on plasma exchange (PLEX) and a combination of simultaneous IVMP and PLEX in neuromyelitis optica spectrum disorders (NMOSD) patients with a severe acute attack.

Method: We conducted a prospective, randomized, controlled, pilot study of the treatments for a severe acute attack in NMOSD patients.

View Article and Find Full Text PDF

Background: Thalassemia trait and G6PD deficiency are asymptomatic and volunteers with these variants are eligible for blood donation.

Aims: This study aimed to investigate prevalence and hematologic profiles of blood donors with thalassemia trait and G6PD deficiency and the influence of these abnormalities have on donor retention and blood component preparation.

Methods: Prospectively recruited blood donors were investigated for thalassemia and G6PD deficiency.

View Article and Find Full Text PDF

Background: Plasma exchange (PLEX) is routinely performed in neuromyelitis optica spectrum disorders (NMOSD) patients with an acute attack who do not respond to corticosteroids treatment.

Objective: To compare treatment outcomes in NMOSD patients with an acute attack between the two groups.

Methods: We retrospectively studied 67 attacks from 52 NMOSD patients.

View Article and Find Full Text PDF

Background: Cell-derived microparticles (MPs) are currently of great interest to screening transfusion donors and blood components. However, the current approach to counting MPs is not affordable for routine laboratory use due to its high cost.

Aim: The current study aimed to investigate the potential use of flow-rate calibration for counting MPs in whole blood, packed red blood cells (PRBCs), and platelet concentrates (PCs).

View Article and Find Full Text PDF