A Randomized, Double-Blind, Split-Face Study of Topical Silymarin vs 2% Hydroquinone Cream in Melasmas.

Background: Hydroquinone is effective in melasma treatment, but side effects may limit its use. Silymarin cream may be a safer alternative.

Objective: To compare the efficacy of 1.

Biological therapy in Psoriasis: An emphasis on its dermatologic adverse events.

Objective: To report an overview of dermatologic adverse events (AEs) related to biologics used for psoriasis and compare common dermatologic AEs across different biologic classes.

Data Source: A comprehensive search in MEDLINE via PubMed from inception through June 9, 2021, was conducted.

Study Selection: The selection process was performed independently by two reviewers.

Successful treatment with ustekinumab of psoriasis vulgaris in a patient undergoing hemodialysis.

Psoriasis is a common chronic inflammatory skin disease but psoriasis patients with renal impairment undergoing dialysis are not frequently seen. Furthermore, the published work contains little information on the treatment with biologic drugs of patients with end-stage renal disease. We describe a 57-year-old man with refractory plaque-type psoriasis and end-stage renal disease due to polycystic kidney disease undergoing hemodialysis.