[Problems in the assessment of the risk from environmental factors on the population's health in the Republic of Kazakhstan].

The paper deals with the evaluation of the influence of environmental factors on human health. It analyzes morbidity rates and their prediction in the biogeochemically exposed area.

[Distribution of heavy metals in organs of experimental animals subjected to dust inhalation].

Biologic substrates of experimental animals characterize mainly overall metals intake and could serve as criteria for environmental pollution degree.

[Autoregulation of brain blood flow in dust bronchitis patients with early cerebral atherosclerosis].

The article deals with brain blood flow autoregulation evaluated through transcranial Doppler study in dust bronchitis patients with early cerebral atherosclerosis in dependence on presence or absence of respiratory failure. Present respiratory failure in these patients causes additional disorders in brain blood flow autoregulation, especially during a stage of early signs of brain circulation insufficiency.

[Using complex of respiratory exercises in miners training].

Using complex of respiratory exercises in occupational selection practice enables better training for work in extreme conditions of coal industry.

[Immunologic reactivity of patients with occupational allergic dermatoses].

The article presents results of examination covering chemical metallurgic plant workers: 41% of the examinees have allergic skin diseases. Findings are that patients with occupational allergic dermatoses have variable degrees of T-immunity suppression.

[Genetic state of population living on soils polluted with heavy metals].

The study covered heavy metals content of soil at various distances from industrial enterprises. The parameters studied are level of micronuclei in peripheral RBC, frequency and spectrum of chromosomal aberrations in WBC of residents. Finding is increased mutation pace induced by mutagens.

[Cytogenetic instability among workers of titanium magnesium production in accordance with work conditions].

Cytogenetic study covered chromosomal aberrations among workers assigned to various occupations of titanium magnesium production. The authors demonstrated various types and increased frequency of chromosomal aberrations. Work conditions appeared to be a factor of induced mutagenesis.

[An assessment of the mental status of miners exposed to the noise load].

The use of psychological-and-diagnostic techniques ant tests designed to study the mental condition and to evaluate the efficiency of psychological adaptation will ensure an early detection of different disorders in the mental status of miners and a differentiation of the population according to their prevalence, which is of a great prognostication importance. The choice of the most informative indices of the miners' psychological status will make it possible to use them in evaluating the professional adaptability of young experts mastering the mining skills, which would maintain a high standard of health and labor longevity.

[The role of inhalation provocation tests in the diagnosis of occupational bronchial asthma].

Light industry female workers suffering from bronchial asthma demonstrated significant pulmonary ventilation disorders of mixed type with prevalent bronchial obstruction. Those changes prove long-standing harm caused by occupational factors. Inhalation provocative tests point out leading role of industrial dust in increased bronchial reactivity.

[The state of the adaptation system of women during the postpartum period under the influence of an industrial complex].

The hormonal status was studied in the dynamics of postpartum stress in the puerperas who lived in the town of Balkhash under the influence of an industrial complex. The puerperas were found to show no pronounced adrenal cortical response to postpartum stress; there was monotony of changes in the content of dopa and dophamine and the levels of adrenaline and noradrenaline remained high on day 5 after delivery as compared with the controls. There were high levels of prolactin and cortisole, which suggests different stress levels in Balkhash females and in the controls.

[Changes in gastric electric activity and serum catecholamine level under the influence of electromagnetic microwaves (experimental studies)].

Chronic experiments on 17 dogs revealed that ultrahigh-frequency electromagnetic waves applied on epigastric area and head induce a double-phase response: depressed electric activity of gaster and increased total catecholamines level during exposure, but higher gastric activity and lower levels of epinephrine and norepinephrine in 24 hours after each of 10 procedures and during 7 days after 10 procedures. Double-phase changes in electric activity of gaster could be explained by double-phase fluctuations of humoral division in chromaffin system.

[Prognostic evaluation of occupational adaptation progress among miners at the coal mines].

Gradual factorial analysis of heart rhythm regulation parameters revealed individual and typological peculiarities of adaptational phases in miners during 20 years. The studies determined dysadaptation time in individuals with cortex-limbic and limbic-stem domination.

[Parameters of oxidative metabolism, neuro-humoral and hormonal regulation in the condensed exhaled air in early stages of anthracosilicosis].

For early diagnosis of anthracosilicosis, the authors studied oxidation parameters, neuromediators and hormones in expired air condensate in coal miners. Premorbid stage of anthracosilicosis is characterized by activated lipids peroxidation, high levels of neuromediators (acetylcholine, catecholamines), tissue hormones (histamine, serotonine) and lower contents of adaptive hormones (cortisol, triiodothyronine, thyroxine).

[The informational significance of metal bioaccumulation in the hair of preschool children].

Hair and urine metal accumulation was studied in healthy children living in different pollution areas. The levels of biogenic amines, the activity of the enzymes LDH, AP, and cholinesterase were also determined in the exhaled air condensate (EAC) and urine. High accumulation of metals, low EAC levels of biogenic amines, high activity of the urine enzymes were observed in the children residing in high polluted areas.