[The reflex and direct actions of novocaine on the rhythm of the heart beats in rats in early postnatal ontogeny].

In experiments on newborn rats it was shown that heart beating frequency depended on the intensity of interoceptive afferentation. Partial shutdown of the afferentation by means of intraperitoneal injection of novocaine in the dose of 25 mg/kg of body weight caused the increase of heart beating and the more complete one at higher doses (100 mg/kg of body weight) led to its decrease. The injection of 2% novocaine (150-200 mg/kg of body weight) into the peritoneum of rat puppies on the first week of life caused the transition of bradycardia into temporary or permanent stop of heart beating.

[The effect of changes in the level of interoceptive afferentation on the spontaneous periodic motor activity of rat pups].

The effect of intraperitoneally injected (25 mg/kg) novocaine (procaine) on the spontaneous periodic motor activity was investigated in rat puppies ageing from 1 to 14 days. It was shown that reactions were phasic: initial continuous and then elevated activity was followed by depression and recovery. The duration and intensity of stimulation and depression decrease with age.

[Water metabolism in monkeys during 14-day anti-orthostatic hypokinesia].

Water balance parameters were measured in hypokinetic rhesus monkeys using tritiated water. During exposure the water content decreased by 18.4%, with 11.

[Establishment of somato-sympathetic reactions during the early stages of postnatal ontogeny in cats].

In adult cats and 1--16--day kittens, repeated stimuli of less than 1/sec and supramaximal strength applied to afferent fibers of nervus ischiadicus evoked the multicomponent responses recorded from efferent fibers of n. hypogastricus. Latencies of responses components decreased during postnatal development.

[The growth of axons in the periphery after a decrease in the quantity of nerve cells in sympathetic ganglia].

The amount of cells in stellate ganglia of rat was decreased by chemical sympathectomy to 30% of the normal amount. At the age of two months sympathectomized rats have no pressor reflexes to asphyxia and femoral nerve stimulation. These responses are restored at the age of four months.

[Age changes in rat vasomotor reflexes and sympathetic neuron ultrastructure following chemical sympathectomy].

Prolonged administration of guanethidine (20 mg/kg) to newborn rats caused a marked reduction in the number of cells in stellate ganglia. The administration of guanethidine for 14 days decreased the amount of cells to 30% of the normal (partial sympathectomy), and for 28 days--to 0.5% (complete sympathectomy).