Atrial Flutter as an Initial Presentation of Malignant Pericardial Effusion Caused by Lung Cancer.

Pericardial effusion is a common cardiac condition that can be lethal if left untreated. Patients who have pericardial effusion often present with dyspnea, chest discomfort, chest tightness, and cough. Cardiac arrhythmia as an initial presentation of pericardial effusion is not common.

Bilateral Popliteal Vein Thrombosis, Acute Pulmonary Embolism and Mild COVID-19.

In 2020, the coronavirus disease 2019 (COVID-19) has become a global health disaster. Patients with COVID-19 have variable clinical features and unpredictable prognoses; the infectious complication may occur in many organs, causing a broad spectrum of symptoms and severity. Pulmonary embolism (PE) is a fatal urgent complication, which may occur following a severe infection.

Pseudo-Appendicitis in an Adolescent With COVID-19.

Coronavirus disease 2019 (COVID-19) pandemic is a global health emergency in 2020. Patients with COVID-19 may present with variable clinical features, involving pulmonary, gastrointestinal, neurological, and cardiovascular symptoms. Notwithstanding, the acute abdomen as a presentation of COVID-19 is rare.

Newly diagnosed diabetes mellitus, DKA, and COVID-19: Causality or coincidence? A report of three cases.

Novel coronavirus disease 2019 (COVID-19), a 2020 pandemic, has resulted in an unexpected loss in lives, quality of life, and the economy. The COVID-19 clinical spectrum varies from asymptomatic to death, and its complications may involve various organs. Notwithstanding, the impact of COVID-19 on endocrine systems is understudied.

Fatal Outcome in a Kidney-Pancreas Transplant Recipient With COVID-19.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious pathogen causing the novel coronavirus disease 2019 (COVID-19), the ongoing unprecedented pandemic in 2020. SARS-CoV-2 primarily targets the respiratory systems, so acute respiratory distress syndrome is the major cause of death. Clinical courses of COVID-19 are variable and unpredictable, while some epidemiologic and clinical factors have been found to have a negative impact on the disease prognosis.

Lithium Toxicity in Two Coronavirus Disease 2019 (COVID-19) Patients.

Coronavirus disease 2019 (COVID-19) is a highly contagious disease, which is currently causing a devastating pandemic resulting in more than millions of infected cases worldwide. Emerging evidence reports the impact of several co-morbidities on the clinical features and outcomes of COVID-19. However, the evidence regarding the association of mental health illnesses and psychiatric treatment on the prognoses of COVID-19 is still lacking.

Hyperpyrexia in patients with COVID-19.

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a global health emergency, in which its effective treatment and prevention remain obscured. Hyperpyrexia is an elevation of body temperature above 106.7°F (41.

Successful Conservative Management of Acute Appendicitis in a Coronavirus Disease 2019 (COVID-19) Patient.

Appendectomy is the gold standard of treatment for acute appendicitis; however, recent evidence suggests conservative management with intravenous antibiotics may provide similar outcomes and can be used as an alternative in selected patients. Performing appendectomy in acute appendicitis patients with 2019 novel Coronavirus Disease (COVID-19) is challenging, as it involves considerable operative risks for the patients and risks for health care professionals (HCPs) exposed to COVID-19. Medical management eliminates the morbidity and mortality associated with surgery but involves significant risks of treatment failures that, in turn, may lead to perforation, peritonitis, and death.

Rhabdomyolysis as a Presentation of 2019 Novel Coronavirus Disease.

An emerging viral infection is a global public health challenge. The development of modern, fast, and extensive transportation makes the outbreak hard to contain. Everyone is at risk, and the outbreak can rapidly turn into a pandemic crisis, like what we are currently facing for the 2019 novel coronavirus disease (COVID-19).

Missed Abortion Presented with Worsening Hyperemesis Gravidarum.

Hyperemesis gravidarum (HG) is the most common cause of in-patient hospitalizations during the first half of pregnancy. The etiology of HG has not yet been elucidated, and the treatment is mainly symptomatic. Untreated severe HG can lead to catastrophic maternal complications such as cardiac arrhythmia and death.

Does Atrial Fibrillation Increase the Risk of Developing End-stage Renal Disease in Patients with Chronic Kidney Disease?

Patients with atrial fibrillation (AF) have elevated risks of developing stroke, heart failure, and myocardial infarction. However, the impact of AF on the progression of chronic kidney disease (CKD) is uncertain. Our review objective is to investigate whether AF increases the risk of developing end-stage renal disease (ESRD) in patients with CKD.

Tension Pneumothorax Following Pneumocystis jirovecii Pneumonia.

Pneumocystis jirovecii pneumonia (PJP) is one of the most common causes of respiratory failure in patients with human immunodeficiency virus (HIV) infection, for which the mortality rate is approximately 10%. Spontaneous pneumothorax as a presentation of PJP has been reported with rising frequency, but tension pneumothorax as a presentation of PJP is rare. We reported a case of a middle-aged male with HIV infection who presented to our hospital with acute worsening shortness of breath and was later diagnosed with tension pneumothorax due to PJP.

miRNA125b Downregulation: A Review of the Novel Paradigm of Psoriasis Epigenetic Regulation.

MicroRNAs (miRNAs) are small, non-protein coding ribonucleic acids (RNAs) that play a critical role in the regulation of gene expression. Change in miRNA expression has been identified in various diseases, including psoriasis. Our narrative review provides an updated overview of current research on miRNA125b and its role in psoriasis pathogenesis.

Gastric Perforation: A Rare Accident from Intubation.

Perforation of a gastrointestinal tract as a complication of intubation is unusual, and only few cases have been reported. Prompt recognition and management of gastrointestinal tract perforation are needed to limit the morbidity and mortality of this condition. We presented a case of an acutely ill patient who developed gastric perforation following difficult intubation to remind clinicians of a life-threatening complication that can develop following a life-saving procedure.

Recurrent Syncope as a Presentation of Pulmonary Embolism.

The diagnosis of pulmonary embolism is challenging particularly when patients present with vague and/or non-specific symptoms and signs. Misdiagnosis of pulmonary embolism can lead to death or severe morbidity. We reported a case of a 60-year-old woman presented with recurrent syncope who later was diagnosed as submassive pulmonary embolism.

Candidate cancer-targeting agents identified by expression-profiling arrays.

Background: One particularly promising component of personalized medicine in cancer treatment is targeted therapy, which aims to maximize therapeutic efficacy while minimizing toxicity. However, the number of approved targeted agents remains limited. Expression microarray data for different types of cancer are resources to identify genes that were upregulated.

Genes associated with the cis-regulatory functions of intragenic LINE-1 elements.

Background: Thousands of intragenic long interspersed element 1 sequences (LINE-1 elements or L1s) reside within genes. These intragenic L1 sequences are conserved and regulate the expression of their host genes. When L1 methylation is decreased, either through chemical induction or in cancer, the intragenic L1 transcription is increased.