[The microhemodynamics and lymph flow in the small intestine under the action of histamine against a background of water loading and hyperthermia in dogs].

In anesthetized dogs, an increase of the lymph flow and the transcapillary fluid transfer, under the effect of histamine, was due to elevation of capillary hydrostatic pressure and capillary filtration coefficient in the small intestine. Against the background of water load and hyperthermia, histamine induced less obvious shifts of the microhemodynamic parameters and lymph flow in the small intestine.

[The dependence of changes in the microhemodynamics and lymph formation in the liver on the level of the arterial and portal blood flows].

In cats, when perfusing hemodynamically isolated liver with a constant blood volume, an increasing of arterial as well as portal blood flows was shown to increase hydrostatic pressure in sinusoids and lymph production in the liver, whereas decreasing of the flows decreased these parameters. The above changes of the blood flows entailed various shifts of sinusoidal hydrostatic pressure and postsinusoidal resistance. When the volume blood flow in the liver artery increased, the coefficient of sinusoidal filtration increased too, whereas an increment of the blood flow in portal vein led to its diminishing.

[Dependence of the parameters of microcirculation and lymph flow in the liver on the value of venous pressure].

In experiments on cats the perfusion (at a constant flow and controlled venous outflow) of haemodynamic isolated liver was carried out. It was shown that at the levels of venous pressure in the liver 0, 2, and 4 mm Hg, the lymph flow (22.8 +/- 3.

[Changes in the transsinusoidal fluid transfer in the cat liver during noradrenaline infusion].

The blood microcirculation and the lymph flow were studied in the cat hemodynamically isolated liver perfused under conditions of a regulated venous outflow and i.a. and intraportal administration of noradrenaline.

[The relation of lymph flow and microcirculation in the cat liver under the effect of serotonin and bradykinin].

In experiments on cats with hemodynamically isolated and perfused wider constant flow liver it was shown that intraarterial or intraportal infusion of serotonin and bradykinin increased a transinusoidal fluid fransher and lymph formation in the region. The elevated franshes walls of maintained mainly by an increase on the permeability of the walls of exchange microvessels. Differences were revealed in the achions of serofouri and bradykinin upon liver's arterial and portal vessels, the sensitivity of portal vein to the drugs being which lesser than of the live artery.

[Lympho- and hemodynamic reactions during the contraction of the skeletal musculature of the hindlimb in dogs].

Alterations in arterial pressure (AP) values, blood and perfusate flow from the thoracic duct, lymph and perfusate flow from the femoral lymphatic vessel during femoral muscle contractions induced by electrical stimulation applied for 1.5 and 3.0 min, were studied: the AP values were decreased by 10-15 mm Hg, the blood flow increased to 293.

[Lymph-blood microcirculatory shifts in the intestines during histamine action].

The infusion of histamine increased the lymph flow in the cat innervated intestine due to squeezing off of the lymph from lymphatic vessels under motor activation of the intestine, followed by an increase in the lymph production because of accelerated transcapillary transfer of fluid from the blood into interstitium. The increase in the water hemato-lymphatic transition was maintained by an augmentation of the capillary filtration coefficient against the background of both a decrease and an increase tin capillary hydrostatic pressure occurring simultaneously with a drop of the perfusion pressure under the effect of histamine. After decentralization of the intestine histamine led to a drop of capillary hydrostatic pressure, leaving the shifts of other parameters the same.

[Lymph flow, micro- and macrohemocirculation in the intestine of cats during infusion of serotonin].

In the cat isolated small intestine perfused with a constant flow, i. a. serotonin (0.

[Coupled functions of vessels and lymph outflow in the cat small intestine during stimulation of the sympathetic nerves].

Experiments in cats with the constant blood volume perfusion of the small intestine vessels revealed constrictor responses of arterial, venous and lymphatic vessels to electrical stimulation of sympathetic nerves, the responses being most obvious at the 8, 10 and 10-20 Hz frequency of stimulation. Activation of sympathetic nerves augmented the pre- and postcapillary resistance of the vessels, the resistance being the greatest at 8 and 10 Hz. Stretching ability of venous vessels decreased.

[Relation of lymph and microcirculation dynamics in the extremities of cats as affected by bradykinin and histamine].

In perfused with constant flow isolated cat hindlimbs, i.a. infusion of 0.

[Macro- and micro-hemocirculatory shifts in the small intestine during pressor reflexes].

In acute experiments on cats, effects of occlusion of common carotid arteries, stimulation of afferent fibers of the brachial plexus, application of acetylcholine to reflexogenous zones of peritoneum and mesentery of the small intestine on macro- and microcirculation of the isolated small intestine perfused under constant flow, were studied. Under effects of occlusion and afferent stimulation, arteries and veins of the small intestine were constricted, whereas in stimulation of abdominal reflexogenous zones their reactions were different. All the reflexes induced augmentation of the capillary hydrostatic pressure, capillary filtration coefficient and post-capillary resistance, whereas decreasing the venous vessels distention.

[Relation between changes in macro- and microcirculation and lymph flow in the extremities of the cat after histamine infusion].

In experiments on the cat isolated hindlimb perfused with a constant flow, it was shown that against the background of dilatation of arteries under effect of histamine, venous outflow from the hindlimb increased after 0.05-0.1 microgram X min-1 X kg-1 histamine and decreased after a higher doses.