Publications by authors named "Kuiying Yu"
Background: The objective of the present study is to comprehensively evaluate the impact of the rs1800975 A/G polymorphism within the human xeroderma pigmentosum group A () gene on susceptibility to overall cancer by performing an integrative analysis of the current evidence.
Methods: We retrieved possible relevant publications from a total of six electronic databases (updated to April 2020) and selected eligible case-control studies for pooled assessment. -values of association and odds ratio (OR) were calculated for the assessment of association effect.
Article Synopsis
- The study explores the genetic impact of three specific CYP4A11 polymorphisms (rs9332978 A/G, rs1126742 T/C, and rs9333025 G/A) on the likelihood of cardiovascular and cerebrovascular diseases.* -
- A meta-analysis of 22 case-control studies was conducted, revealing that rs9332978 was linked to a higher risk of these diseases, particularly in individuals with hypertension, while rs1126742 showed significant differences in risk across various populations.* -
- The findings suggest that rs1126742 is a notable risk factor for hypertension in Caucasians, and that the AG genotype of rs9332978 increases disease risk, whereas the AA genotype of rs9333025 may
Background: Inconsistent conclusions have been reported for the genetic relationship between CYP4F2 (Cytochrome P450 Family 4 Subfamily F Member 2) polymorphisms and the susceptibility to cardiovascular and cerebrovascular diseases.
Methods: We performed a meta-analysis to assess the potential role of rs1558139 C/T and rs2108622 G/A polymorphisms of CYP4F2 in the risks of cardiovascular and cerebrovascular diseases. The retrieval of four databases, including PubMed, Web of Science (WOS), China National Knowledge Infrastructure (CNKI) and WANFANG DATA, was conducted.
[Effects of puerarin on the neurocyte apoptosis and p-Akt (Ser473) expressions in rats with cerebral ischemia/reperfusion injury].
Zhongguo Zhong Xi Yi Jie He Za Zhi
August 2012
Objective: To observe the effects of puerarin (Pue) on the neurocyte apoptosis and the p-Akt (Ser473) expression in the ischemic penumbra of rats with cerebral ischemia/reperfusion (I/R).
Methods: The 48 Sprague-Dawley rats were randomly divided into four groups, i.e.