Nuclear magnetic resonance-based serum metabolic profiling of dairy cows with footrot.

Footrot is a debilitating and contagious disease in dairy cows, caused by the Gram-negative anaerobe Dichelobacter nodosus. H-NMR (nuclear magnetic resonance)-based metabolomics has been previously used to understand the pathology and etiology of several diseases. The objective of this study was to characterize serum from dairy cows with footrot (n=10) using H-NMR-based metabolomics and chemometric analyses.