Transcription factor ETS1‑mediated ECT2 expression promotes the malignant behavior of prostate cancer cells.

Prostate cancer remains the most prevalent malignancy diagnosed in men worldwide. Epithelial cell transforming sequence 2 (ECT2) is an oncogene involved in the progression of human tumors. The present study aimed to explore the involvement of ECT2 in prostate cancer and its participation in the malignant progression of prostate cancer.

Interactions with compliant loads alter stretch reflex gains but not intermuscular coordination.

The human motor system regulates arm mechanics to produce stable postures during interactions with different physical environments. This occurs partly via involuntary mechanisms, including stretch reflexes. Previous single-joint studies demonstrated enhanced reflex sensitivity during interactions with compliant environments, suggesting reflex gain increases to enhance limb stability when that stability is not provided by the environment.

Regulation of multijoint stretch reflexes during interactions with stiff and compliant environments.

The purpose of this study was to examine how multijoint stretch reflexes are modulated during interactions with stiff and compliant environments. Reflex responses were elicited using a 3D robotic manipulator to perturb arm posture in the three degrees of freedom relevant to functional behaviors. The robot applied controlled displacements and simulated environments with different stiffnesses.

Bilateral vestibular loss leads to active destabilization of balance during voluntary head turns in the standing cat.

The purpose of this study was to determine the source of postural instability in labyrinthectomized cats during lateral head turns. Cats were trained to maintain the head in a forward orientation and then perform a rapid, large-amplitude head turn to left or right in yaw, while standing freely on a force platform. Head turns were biomechanically complex with the primary movement in the yaw plane accompanied by an ipsilateral ear-down roll and nose-down pitch.