Publications by authors named "Kuerbannisa Wulayin"
Introduction: The hepatitis C virus (HCV) poses a major global health challenge, with its non-structural proteins being essential for viral replication and pathogenesis. Mutations in these proteins significantly contribute to drug resistance, necessitating innovative therapeutic strategies. This study aims to identify epitope-based therapeutic targets in the non-structural proteins of HCV genotype 1, employing in-depth in silico tools to counteract emerging drug resistance.
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- The study examines the potential of fatty acid binding protein 1 (FABP1) as a serum biomarker for liver injury in chronic hepatitis B virus (HBV) patients.
- Research was conducted on 293 patients, showing that FABP1 levels in serum were significantly higher in those with chronic HBV-related diseases compared to healthy controls, especially as the disease progressed.
- A notable negative correlation was found between FABP1 expression and liver inflammation grades, indicating its potential role in monitoring disease progression, though no correlation with fibrosis was observed.