Publications by authors named "Kuendig T"

Lichen planus (LP) is a highly prevalent inflammatory skin disease. While various clinical subtypes have been defined, detailed comparisons of these variants are lacking. This study aimed to elucidate differences in gene expression and cellular composition across LP subtypes.

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Article Synopsis
  • * This study focused on bead-on-plate welding of 0.2 mm thick pure copper using a blue diode laser, testing specific power, speed, and angle settings to achieve full penetration welds without defects.
  • * Results showed that using certain parameters produced stronger and more ductile welds, with the best performing settings (Cu-1) yielding mechanical properties close to unwelded copper, offering a reliable alternative for joining small, thin parts.
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Propionibacterium acnes is a Gram-positive commensal bacterium thought to be involved in the pathogenesis of acne vulgaris. Although the ability of P. acnes in the initiation of pro-inflammatory responses is well documented, little is known about adaptive immune responses to this bacterium.

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Using the technique of homologous recombination in embryonic stem cells, a mouse strain without functional CD4 and CD8 genes has been generated. Surprisingly, these mice contain significant numbers of alpha beta T cells. Although mice deficient for CD8 only do not show any cytotoxic response when their T cells are stimulated with either alloantigen or viral antigen, the CD4-8- mice do generate alloreactive cytotoxic T cells.

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